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Thiomalic acid is an intermediate in the synthesis of corrosion inhibitors, soil fumigants, active pharmaceutical ingredients, and electroplating agents. [1] The sodium and gold salt of thiomalic acid, sodium aurothiomalate, is used as a pharmaceutical drug for the treatment of rheumatoid arthritis. [2]
Succimer is an isomer of 2,3-dimercaptosuccinic acid. 2,3-dimercaptosuccinic acid is the organosulfur compound with the formula HO 2 CCH(SH)CH(SH)CO 2 H. This colorless solid contains two carboxylic acid and two thiol groups, the latter being responsible for its mildly unpleasant odour.
Thioglycolic acid with a pK a of 3.83 [7] is an acid about 8.5 times stronger than acetic acid (pK a 4.76): HSCH 2 CO 2 H → HSCH 2 CO 2 − + H + The second ionization has a pK a of 9.3: HSCH 2 CO 2 − → − SCH 2 CO 2 − + H + Thioglycolic acid is a reducing agent, especially at higher pH.
The name mercapturic acid is a combination of mercapturic and acid. The latter indicates that the compound is an acid. The former is a compound word consisting of the stem mercaptur-, coming from mercaptan, and the suffix-ic, meaning "having the character of". In sum, the name mercapturic acid means "an acid with mercaptan character/nature". [6]
3-Mercaptopropionic acid (3-MPA) is an organosulfur compound with the formula HSCH 2 CH 2 CO 2 H. It is a bifunctional molecule, containing both carboxylic acid and thiol groups. It is a colorless oil.
Mercaptopurine (6-MP), sold under the brand name Purinethol among others, is a medication used for cancer and autoimmune diseases. [2] Specifically it is used to treat acute lymphocytic leukemia (ALL), acute promyelocytic leukemia (APL), Crohn's disease, and ulcerative colitis.
Isocarboxazid (Marplan, Marplon, Enerzer) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class used as an antidepressant. [6] Along with phenelzine and tranylcypromine, it is one of only three classical MAOIs still available for clinical use in the treatment of psychiatric disorders in the United States, [7] [8] though it is not as commonly employed in ...
Non-competitive inhibition is a type of enzyme inhibition where the inhibitor reduces the activity of the enzyme and binds equally well to the enzyme whether or not it has already bound the substrate. [1] This is unlike competitive inhibition, where binding affinity for the substrate in the enzyme is decreased in the presence of an inhibitor.