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Technetium-99m (Tc-99m) can be readily detected in the body by medical equipment because it emits 140.5 keV gamma rays (these are about the same wavelength as emitted by conventional X-ray diagnostic equipment), and its half-life for gamma emission is six hours (meaning 94% of it decays to 99 Tc in 24 hours). Besides, it emits virtually no beta ...
Technetium-99 (99 Tc) is an isotope of technetium which decays with a half-life of 211,000 years to stable ruthenium-99, emitting beta particles, but no gamma rays. It is the most significant long-lived fission product of uranium fission, producing the largest fraction of the total long-lived radiation emissions of nuclear waste .
A Tc-99m pertechnetate solution is being eluted from Mo-99 molybdate bound to a chromatographic substrate. A technetium-99m generator, or colloquially a technetium cow or moly cow, is a device used to extract the metastable isotope 99m Tc of technetium from a decaying sample of molybdenum-99.
97m Tc is the most stable, with a half-life of 91.0 days (0.097 MeV). [4] This is followed by 95m Tc (half-life: 61 days, 0.038 MeV) and 99m Tc (half-life: 6.04 hours, 0.143 MeV). 99m Tc only emits gamma rays, subsequently decaying to 99 Tc. [7] For isotopes lighter than 98 Tc, the primary decay mode is electron capture to isotopes of molybdenum.
A nuclear pharmacist adds anywhere from 50 - 100 mCi of Na[99m TcO 4] to the reaction vial to make the final product, in the pH range of 3.8 to 8.0. After being allowed to react at room temperature for 15 minutes to ensure maximum labeling of the human albumin with 99m Tc, the kit can then be diluted with sterile normal saline as needed.
Technetium (99m Tc) sestamibi ("Cardiolite") is widely used for imaging of the heart. Technetium forms a variety of coordination complexes with organic ligands. Many have been well-investigated because of their relevance to nuclear medicine. [54] Technetium forms a variety of compounds with Tc–C bonds, i.e. organotechnetium complexes.
Many radiopharmaceuticals use technetium-99m (Tc-99m) which has many useful properties as a gamma-emitting tracer nuclide. In the book Technetium a total of 31 different radiopharmaceuticals based on Tc-99m are listed for imaging and functional studies of the brain, myocardium, thyroid, lungs, liver, gallbladder, kidneys, skeleton, blood and ...
Technetium (99m Tc) sestamibi is a lipophilic cation which, when injected intravenously into a patient, distributes in the myocardium proportionally to the myocardial blood flow. Single photon emission computed tomography imaging of the heart is performed using a gamma camera to detect the gamma rays emitted by the technetium-99m as it decays.