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DESeq2 is a software package in the field of bioinformatics and computational biology for the statistical programming language R. It is primarily employed for the analysis of high-throughput RNA sequencing (RNA-seq) data to identify differentially expressed genes between different experimental conditions.
Within computational biology, an MA plot is an application of a Bland–Altman plot for visual representation of genomic data. The plot visualizes the differences between measurements taken in two samples, by transforming the data onto M (log ratio) and A (mean average) scales, then plotting these values.
The aim behind the choice of a variance-stabilizing transformation is to find a simple function ƒ to apply to values x in a data set to create new values y = ƒ(x) such that the variability of the values y is not related to their mean value.
fastqp Simple FASTQ quality assessment using Python. Kraken: [9] A set of tools for quality control and analysis of high-throughput sequence data. HTSeq [10] The Python script htseq-qa takes a file with sequencing reads (either raw or aligned reads) and produces a PDF file with useful plots to assess the technical quality of a run.
Feature scaling is a method used to normalize the range of independent variables or features of data. In data processing , it is also known as data normalization and is generally performed during the data preprocessing step.
In morphology and lexicography, a lemma is the canonical form of a set of words. In English, for example, run, runs, ran, and running are forms of the same lexeme, so we can select one of them; ex. run, to represent all the forms. Lexical databases such as Unitex use this kind of representation.
Denormalization is a strategy used on a previously-normalized database to increase performance. In computing, denormalization is the process of trying to improve the read performance of a database, at the expense of losing some write performance, by adding redundant copies of data or by grouping data.
In mathematics, the Smith normal form (sometimes abbreviated SNF [1]) is a normal form that can be defined for any matrix (not necessarily square) with entries in a principal ideal domain (PID). The Smith normal form of a matrix is diagonal , and can be obtained from the original matrix by multiplying on the left and right by invertible square ...