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Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. [1] Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell (cytotoxicity) or an organ such as the liver (hepatotoxicity).
This type of adverse effect that results from pharmaceutical drug exposure is commonly due to interactions of the drug with its intended target. In this case, both the therapeutic and toxic targets are the same. To avoid toxicity during treatment, many times the drug needs to be changed to target a different aspect of the illness or symptoms.
A toxicologist working in a lab (United States, 2008)Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms [1] and the practice of diagnosing and treating exposures to toxins and toxicants.
The journal is abstracted and indexed in EMBASE, EMBiology, and Scopus. According to the Journal Citation Reports, the journal has a 2014 impact factor of 2.031, ranking it 56th out of 87 journals in the category "Toxicology" [4] and 146th out of 254 journals in the category "Pharmacology & pharmacy". [5]
As of 2023, Annual Review of Pharmacology and Toxicology is being published as open access, under the Subscribe to Open model. [1] As of 2024, Journal Citation Reports lists the journal's 2023 impact factor as 11.2, ranking it second of 106 journal titles in the category "Toxicology" and ninth of 354 titles in the category "Pharmacology ...
BMC Pharmacology and Toxicology is a peer-reviewed open-access scientific journal that covers the field of pharmacology and toxicology, focusing on areas such as drug action, toxicology, and clinical pharmacology. [1] The journal is published by BioMed Central.
Toxicology and Applied Pharmacology is a semi-monthly peer-reviewed scientific journal covering research pertaining to the action of chemicals, drugs, or natural products on animals or humans. The journal covers mechanistic approaches to the physiological , biochemical , cellular , or molecular understanding of toxicologic and pathologic ...
International Journal of Toxicology is abstracted and indexed in, among other databases: SCOPUS, and the Social Sciences Citation Index.According to the Journal Citation Reports, its 2016 impact factor is 1.205, ranking it 86 out of 92 journals in the category 'Toxicology' [1] and 213 out of 256 journals in the category 'Pharmacology & Pharmacy'.