Ads
related to: periodic counter current chromatography
Search results
Results from the WOW.Com Content Network
Periodic counter-current chromatography (PCC) is a method for running affinity chromatography in a quasi-continuous manner. Today, the process is mainly employed for the purification of antibodies in the biopharmaceutical industry [ 1 ] as well as in research and development.
A high-performance countercurrent chromatography system. Countercurrent chromatography (CCC, also counter-current chromatography) is a form of liquid–liquid chromatography that uses a liquid stationary phase that is held in place by inertia of the molecules composing the stationary phase accelerating toward the center of a centrifuge due to centripetal force [1] and is used to separate ...
In contrast to Counter current chromatography (see above), periodic counter-current chromatography (PCC) uses a solid stationary phase and only a liquid mobile phase. It thus is much more similar to conventional affinity chromatography than to counter current chromatography.
The advantage compared to single column setups is that the resin material can be fully loaded since non-binding product is directly passed on to a consecutive column with fresh column material. These chromatographic processes are known as periodic counter-current chromatography (PCC). The resin costs per amount of produced product can thus be ...
Periodic counter-current chromatography, a type of affinity chromatography; Portable C Compiler, an early compiler for the C programming language; Precipitated calcium carbonate, a chemical compound; Proof-carrying code, a software mechanism that allows a host system to verify properties; Pyridinium chlorochromate, a yellow-orange salt
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Donate
Paper chromatography; Partition chromatography; Partition equilibrium; Periodic counter-current chromatography; Post-column oxidation–reduction reactor; Process analytical chemistry; Purnell equation
A typical mAb purification process is shown at right. Albeit the long history of protein A chromatography for the production of antibodies, the process is still being improved today. Continuous chromatography, more precisely periodic counter-current chromatography, enormously increases the productivity of the purification step.
Ads
related to: periodic counter current chromatography