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Metformin does not cause kidney damage by itself, however there is a risk of serious side effects if metformin is used when you have impaired renal function, Dr. Gupta notes.
Metformin is generally safe in people with mild to moderate chronic kidney disease, with a proportional reduction of metformin dose according to severity of estimated glomerular filtration rate (eGFR) and with periodic assessment of kidney function, (e.g., periodic plasma creatinine measurement). [92]
While it was once “just” a medication for people with type 2 diabetes, metformin is now thought of as a “wonder drug with multiple potentials,” says David Cutler, M.D., a family medicine ...
Metformin is the most commonly prescribed oral drug for diabetes. Of course, if you or a loved one receives treatment for diabetes, you probably already knew this. 7 Benefits of Metformin ...
One rare (about 1% chance) but serious side affect of metformin is that it can cause lactic acidosis, usually in patients with poor kidney function. [35] Sometimes, practitioners will slowly increase the dose of the medication to help with tolerance to the medication.
Metformin should not be used in those with severe kidney or liver problems. [24] The American Diabetes Association and European Association for the Study of Diabetes recommend using a GLP-1 receptor agonist or SGLT2 inhibitor as the first-line treatment in patients who have or are at high risk for atherosclerotic cardiovascular disease , heart ...
A smaller study on metformin also found that the average weight lost in 154 patients was between 5.6 and 7 kilograms — or 13 to 15 pounds. ... Kidney disease. Pancreatitis.
Although it must be used with caution in patients with impaired liver or kidney function, Metformin, a biguanide, has become the most commonly used agent for type 2 diabetes in children and teenagers. Among common diabetic drugs, Metformin is the only widely used oral drug that does not cause weight gain. [9]
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