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Pepto-Bismol is an over-the-counter drug currently produced by the Procter & Gamble company in the United States, Canada and the United Kingdom. Pepto-Bismol is made in chewable tablets [ 24 ] and swallowable caplets, [ 25 ] but it is best known for its original formula, which is a thick liquid.
The active ingredient in Kaopectate has changed since its original creation. Originally, kaolinite was used as the adsorbent and pectin as the emollient. Attapulgite (a type of absorbent clay) replaced the kaolinite in the 1980s, but was banned by the U.S. Food and Drug Administration in a ruling made in April 2003.
Antimotility agents are drugs used to alleviate the symptoms of diarrhea. These include loperamide (Imodium), bismuth subsalicylate (Pepto-Bismol), [1] diphenoxylate with atropine (Lomotil), and opiates such as paregoric, tincture of opium, codeine, and morphine.
Electrolyte solutions, while not true antidiarrheals, are used to replace lost fluids and salts in acute cases.; Bulking agents like methylcellulose, guar gum or plant fibre (bran, sterculia, isabgol, etc.) are used for diarrhoea in functional bowel disease and to control ileostomy output.
Bismuth subsalicylate is used to treat diarrhea; [9] it is the active ingredient in such "pink bismuth" preparations as Pepto-Bismol, as well as the 2004 reformulation of Kaopectate. It is also used to treat some other gastro-intestinal diseases like shigellosis [ 72 ] and cadmium poisoning . [ 9 ]
It is an active ingredient in stomach-relief aids such as Pepto-Bismol and some formulations of Kaopectate. Other derivatives include methyl salicylate , used as a liniment to soothe joint and muscle pain, and choline salicylate , which is used topically to relieve the pain of mouth ulcers .
Pepto-Bismol over-the-counter drug for minor digestive system upset (acquired as part of Norwich Eaton Pharmaceuticals in 1982) Prilosec OTC (licensed from AstraZeneca) Rolaids (acquired in 2024 from Lil' Drug Store Products) Sangobion (acquired from Merck Group) Scope mouthwash; Seven Seas (acquired from Merck Group) Vicks cough and cold products
Dose – For children, 5 to 20 drops, adults, 1 to 2 tea-spoons. The Medical Companion, Or Family Physician , a book from 1827, gave the following recipe: Paregoric Elixir – Take of purified opium, flowers of Benzoin, camphor, and essential oil of annis-seed, each, two drachms; brandy, two pints.
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