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Bismuth produces other bismuth salts, which blocks the binding and proliferation of bacteria in stomach mucosal cells, leading to a decrease in inflammation in the intestine. [9] Also, BSS inhibits cyclooxygenase enzyme and leads to a decrease in the production of prostaglandins, which are compounds that increase intestinal inflammation and ...
Early symptoms of lead poisoning in adults are commonly nonspecific and include depression, loss of appetite, intermittent abdominal pain, nausea, diarrhea, constipation, and muscle pain. [36] Other early signs in adults include malaise , fatigue, decreased libido , and problems with sleep. [ 30 ]
Bismuth subcitrate potassium is a salt of bismuth (Bi 3+), potassium (K +) and citrate (C 6 H 4 O 4− 7) in a molar ratio of about 1:5:2, with 3 moles of water. It contains about 25.6% (mass percent) bismuth, which is the active moiety, and 22.9% potassium. [3] [4] Other sources give somewhat different ratios of the constituents.
Bismuth sulfide is a highly insoluble black salt, and the discoloration seen is temporary and harmless. Long-term use (more than six weeks) may lead to accumulation and toxicity. [8] High daily intake over a period of months can possibly cause severe fatigue, weakness and neurological symptoms that reverse with discontinuation. [9]
Bismuth poisoning can occur and has according to some reports been common in relatively recent times. [108] [110] As with lead, bismuth poisoning can result in the formation of a black deposit on the gingiva, known as a bismuth line. [111] [112] [113] Poisoning may be treated with dimercaprol; however, evidence for benefit is unclear. [114] [115]
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Constipation is a bowel dysfunction that makes bowel movements infrequent or hard to pass. [2] The stool is often hard and dry. [4] Other symptoms may include abdominal pain, bloating, and feeling as if one has not completely passed the bowel movement. [3]
The American Cancer Society recently reported an increase in colorectal cancer rates among people under age 55 since the mid-1990s, and the nonprofit estimated there would be 106,590 new cases of ...