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An epiphyseal line is an epiphyseal plate that has become ossified. [1] The process of it forming from an epiphyseal plate is named epiphyseal closure . [ 2 ] In adult humans, it marks the point of fusion between the epiphysis and the metaphysis .
The epiphyseal plate, epiphysial plate, physis, or growth plate is a hyaline cartilage plate in the metaphysis at each end of a long bone.It is the part of a long bone where new bone growth takes place; that is, the whole bone is alive, with maintenance remodeling throughout its existing bone tissue, but the growth plate is the place where the long bone grows longer (adds length).
[3] [4] Between the epiphysis and diaphysis (the long midsection of the long bone) lies the metaphysis, including the epiphyseal plate (growth plate). During formation of the secondary ossification center, vascular canals (epiphysial canals) stemming from the perichondrium invade the epiphysis, supplying nutrients to the developing secondary ...
The longitudinal growth of long bones is a result of endochondral ossification at the epiphyseal plate. Bone growth in length is stimulated by the production of growth hormone (GH), a secretion of the anterior lobe of the pituitary gland.
Primary endochondral ossification begins with the formation of a chondrocyte template. Afterwards, chondrocytes undergo hypertrophy beginning from the mid-diaphysis, eventually extending to the epiphyseal poles, vasculature invades the forming bone transporting mesenchymal stromal cells and hypertrophic cells undergo apoptosis. Mesenchymal ...
The metaphysis (pl.: metaphyses) is the neck portion of a long bone between the epiphysis and the diaphysis. [1] It contains the growth plate, the part of the bone that grows during childhood, and as it grows it ossifies near the diaphysis and the epiphyses.
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The epiphyseal arteries and osteogenic cells invade the epiphysis, depositing osteoclasts and osteoblasts which erode the cartilage and build bone, respectively. This occurs at both ends of long bones but only one end of digits and ribs. Microscopic image of the growth plate