enow.com Web Search

Search results

  1. Results from the WOW.Com Content Network
  2. Lymphocyte - Wikipedia

    en.wikipedia.org/wiki/Lymphocyte

    A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. [1] Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for humoral, antibody-driven adaptive immunity), [2] [3] and innate lymphoid cells (ILCs; "innate T cell-like" cells involved in mucosal immunity and homeostasis), of which natural killer cells are an ...

  3. B cell - Wikipedia

    en.wikipedia.org/wiki/B_cell

    Of the three B cell subsets, FO B cells preferentially undergo T cell-dependent activation while MZ B cells and B1 B cells preferentially undergo T cell-independent activation. [ 16 ] B cell activation is enhanced through the activity of CD21 , a surface receptor in complex with surface proteins CD19 and CD81 (all three are collectively known ...

  4. Plasma cell - Wikipedia

    en.wikipedia.org/wiki/Plasma_cell

    The T cell-dependent processes are subdivided into primary and secondary responses: a primary response (meaning that the T cell is present at the time of initial contact by the B cell with the antigen) produces short-lived cells that remain in the extramedullary regions of lymph nodes; a secondary response produces longer-lived cells that ...

  5. Lymph node - Wikipedia

    en.wikipedia.org/wiki/Lymph_node

    They present the antigen to T cells and, if there is a T cell with the appropriate T cell receptor, it will be activated. [25] B cells acquire antigen directly from the afferent lymph. If a B cell binds its cognate antigen it will be activated. Some B cells will immediately develop into antibody secreting plasma cells, and secrete IgM.

  6. Germinal center - Wikipedia

    en.wikipedia.org/wiki/Germinal_center

    Additionally, the T cells are able to help the B cells by the interaction of the T cell CD40 ligand with the B cell CD40 molecule, which causes a signaling cascade that is beneficial for the survival and proliferation of B cells. B cell receptor activation results in the activation of the NF-kB signaling pathway, which is essential for the ...

  7. Polyclonal B cell response - Wikipedia

    en.wikipedia.org/wiki/Polyclonal_B_cell_response

    The entire mechanism ensures that an activated T cell only stimulates a B cell that recognizes the antigen containing the same epitope as recognized by the T cell receptor of the "costimulating" T helper cell. The B cell gets stimulated, apart from the direct costimulation, by certain growth factors, viz., interleukins 2, 4, 5, and 6 in a ...

  8. Clonal selection - Wikipedia

    en.wikipedia.org/wiki/Clonal_selection

    In immunology, clonal selection theory explains the functions of cells of the immune system (lymphocytes) in response to specific antigens invading the body. The concept was introduced by Australian doctor Frank Macfarlane Burnet in 1957, in an attempt to explain the great diversity of antibodies formed during initiation of the immune response .

  9. Follicular B helper T cells - Wikipedia

    en.wikipedia.org/wiki/Follicular_B_helper_T_cells

    Follicular helper T cells (also known as T follicular helper cells and abbreviated as T FH), are antigen-experienced CD4 + T cells found in the periphery within B cell follicles of secondary lymphoid organs such as lymph nodes, spleen and Peyer's patches, and are identified by their constitutive expression of the B cell follicle homing receptor CXCR5. [1]