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Antiretroviral drugs are used to manage HIV/AIDS.Multiple antiretroviral drugs are often combined into a single pill in order to reduce pill burden.. Some of these combinations are complete single-tablet regimens; the others must be combined with additional pills to make a treatment regimen.
A 2016 advertisement from NIAID promoting the advancement of single-pill antiretroviral drug combinations. In 2000 drug companies have worked together to combine these complex regimens into single-pill fixed-dose combinations. [23] More than 20 antiretroviral fixed-dose combinations have been developed.
STRs are created through combining three antiretroviral drugs into one pill. Single-tablet regimens are only available at specific clinics around the world—meaning there is limited access to these regimens—and are only prescribed if a doctor feels a patient will struggle with the treatment schedule of antiretroviral therapy.
Gilead's Once-Daily Single Tablet Regimen Stribild TM Maintains High Viral Suppression Through Two Years of Therapy Among Treatment-Naïve HIV Patients -- Pivotal Data from Two Phase 3 Studies ...
Gilead's Single Tablet HIV Regimen Stribild ® Demonstrates Durable Viral Suppression Through Three Years of Therapy -- Long-Term Data In Treatment-Naïve Patients Highlight Stribild's Sustained ...
The ongoing study compares a once-daily single tablet regimen containing TAF 10 mg/elvitegravir 150 mg/cobicistat 150 mg/emtricitabine 200 mg with Stribild TM (elvitegravir 150 mg/cobicistat 150 ...
As of 2019, it is listed by the World Health Organization (WHO) as the first-line treatment for adults with HIV/AIDS, with tenofovir/lamivudine/efavirenz as an alternative. [2] It may be used in people with both HIV and tuberculosis , however if the person is on rifampicin a larger dose of dolutegravir is needed.
Gilead's Tenofovir Alafenamide (TAF)-Based Single Tablet HIV Regimen Maintains High Viral Suppression Through 48 Weeks in Phase 2 Study -- Efficacy Similar to Stribild ® , with Favorable Safety ...
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