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This is then released into the blood by the liver where it travels mainly to the muscle cells (95% of the body's creatine is in muscles), and to a lesser extent the brain, heart, and pancreas. Once inside the cells it is transformed into phosphocreatine by the enzyme complex creatine kinase .
An individual administered tubocurarine chloride will be unable to move any voluntary muscles, including the diaphragm. A large enough dose will therefore result in death from respiratory failure unless artificial ventilation is initiated. The LD 50 for mice and rabbits are 0.13 mg/kg and 0.146 mg/kg intravenously, respectively. It releases ...
The muscular system is an organ system consisting of skeletal, smooth, and cardiac muscle. It permits movement of the body, maintains posture, and circulates blood throughout the body. [1] The muscular systems in vertebrates are controlled through the nervous system although some muscles (such as the cardiac muscle) can be
The tone of respiratory muscle is believed to be modulated by muscle spindles via a reflex arc involving the spinal cord. Drugs can greatly influence the rate of respiration. Opioids and anesthetics tend to depress ventilation, by decreasing the normal response to raised carbon dioxide levels in the arterial blood.
Skeletal muscle (commonly referred to as muscle) is one of the three types of vertebrate muscle tissue, the others being cardiac muscle and smooth muscle. They are part of the voluntary muscular system [ 1 ] and typically are attached by tendons to bones of a skeleton .
Yet, curare poisoning mimics total locked-in syndrome in that there is paralysis of every voluntarily controlled muscle in the body (including the eyes), making it practically impossible for the victim to confirm consciousness while paralyzed. [39]
Smooth muscle is grouped into two types: single-unit smooth muscle, also known as visceral smooth muscle, and multiunit smooth muscle. Most smooth muscle is of the single-unit type, and is found in the walls of most internal organs (viscera); and lines blood vessels (except large elastic arteries), the urinary tract , and the digestive tract .
Muscle is a soft tissue, one of the four basic types of animal tissue. Muscle tissue gives skeletal muscles the ability to contract. Muscle is formed during embryonic development, in a process known as myogenesis. Muscle tissue contains special contractile proteins called actin and myosin which interact to cause movement.