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The hollow inner part of a body organ (such as the gastrointestinal tract) or tube (such as an artery) is called the lumen. The side of a cell facing the lumen is called the apical surface; the opposite side, facing away from the lumen is the basolateral surface, which faces instead towards the interstitium, and away from the lumen.
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Properly, this terminology would apply only to an organism that is always planktonic (not normally attached to a surface), although the term can also be applied to one that is sessile (normally attached to a surface). [64] A cluster of Euplectella aspergillum sponges (Venus flower baskets), showing the apical–basal axes
An apical (or medial or subclavicular) group of six to twelve glands is situated partly posterior to the upper portion of the pectoralis minor and partly above the upper border of this muscle. Its only direct territorial afferents are those that accompany the cephalic vein , and one that drains the upper peripheral part of the mamma .
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The brush border on the apical surface of the epithelial cells is covered with glycocalyx, which is composed of oligosaccharides attached to membrane glycoproteins and glycolipids. [7] TEM image of a thin section cut through an epithelial cell showing the luminal surface (apical end) of the cell packed with microvilli that make up the absorbing ...
Epithelial cells feature distinct 'apical', 'lateral' and 'basal' plasma membrane domains. Epithelial cells connect to one another via their lateral membranes to form epithelial sheets that line cavities and surfaces throughout the animal body. Each plasma membrane domain has a distinct protein composition, giving them distinct properties and ...
Tight junctions also help maintain the apicobasal polarity of cells by preventing the lateral diffusion of integral membrane proteins between the apical and lateral/basal surfaces, allowing the specialized functions of each surface (for example receptor-mediated endocytosis at the apical surface and exocytosis at the basolateral surface) to be ...