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  2. Empagliflozin - Wikipedia

    en.wikipedia.org/wiki/Empagliflozin

    Empagliflozin is an inhibitor of the sodium glucose co-transporter-2 (SGLT-2), and works by increasing sugar loss in urine. [2] Empagliflozin was approved for medical use in the United States and in the European Union in 2014. [13] [23] [24] It is on the World Health Organization's List of Essential Medicines. [25]

  3. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    Empagliflozin, approved in the United States in August 2014, under the brand name Jardiance by Boehringer Ingelheim. [30] Of the gliflozins, empagliflozin and tofogliflozin have the highest specificity for SGLT2 inhibition. [1] This oral medicine for type 2 diabetes has been shown to reduce the risk of cardiovascular death. [31]

  4. Empagliflozin/metformin - Wikipedia

    en.wikipedia.org/wiki/Empagliflozin/metformin

    In the European Union empagliflozin/metformin is indicated in adults aged 18 years and older with type 2 diabetes mellitus as an adjunct to diet and exercise to improve glycemic control: [6] in adults inadequately controlled on their maximally tolerated dose of metformin alone; [6]

  5. Type 2 diabetes: Roche says its weekly drug works ... - AOL

    www.aol.com/2009/12/02/type-2-diabetes-roche...

    The $5 billion U.S. diabetes drug market just got a little more competitive. Swiss drugmaker Roche (RHHBY) said Wednesday an experimental medicine in late-stage development works better in ...

  6. Biden targets diabetes drug Jardiance, blood thinner Eliquis ...

    www.aol.com/finance/biden-targets-diabetes-drug...

    The diabetes treatments Jardiance from Eli Lilly and Co. and Merck's Januvia made the list, along with Amgen’s autoimmune disease treatment Enbrel. Other drugs include Entresto from Novartis ...

  7. FDA Rejects Eli Lilly's Diabetes Drug Empagliflozin - AOL

    www.aol.com/news/2014-03-05-fda-rejects-eli...

    Eli Lilly and Boehringer Ingelheim Pharmaceuticals said today that the Food and Drug Administration rejected empagliflozin, the most recent drug to come out of the companies' diabetes partnership.

  8. Diabetes medication - Wikipedia

    en.wikipedia.org/wiki/Diabetes_medication

    Sulfonylureas are useful only in type 2 diabetes, as they work by stimulating endogenous release of insulin. They work best with patients over 40 years old who have had diabetes mellitus for under ten years. They cannot be used with type 1 diabetes, or diabetes of pregnancy. They can be safely used with metformin or glitazones.

  9. Discovery and development of gliflozins - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Medieval physicians routinely tasted urine and wrote discourses on their observations. Which physician originally thought that diabetes mellitus was a renal disorder because of glucose discharged in urine is apparently now lost to history. The discovery of insulin eventually led to a diabetes management focus on the pancreas.

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