Search results
Results from the WOW.Com Content Network
Helminthiasis, also known as worm infection, is any macroparasitic disease of humans and other animals in which a part of the body is infected with parasitic worms, known as helminths. There are numerous species of these parasites , which are broadly classified into tapeworms , flukes , and roundworms .
Arpraziquantel ((R)-praziquantel) is the eutomer (the biologically active enantiomer) of praziquantel, and is a medication which is currently under investigation for the treatment of schistosomiasis in young children since it has less side effects than the usual racemic mixture formulation of praziquantel.
Melarsoprol (for treatment of sleeping sickness caused by Trypanosoma brucei) Eflornithine (for sleeping sickness) Metronidazole (for vaginitis caused by Trichomonas) Tinidazole (for intestinal infections caused by Giardia lamblia) Miltefosine (for the treatment of visceral and cutaneous leishmaniasis, currently undergoing investigation for ...
Praziquantel is not licensed for use in humans in the UK, but it can be imported when necessary on a named-patient basis. [36] It is available in the UK as a veterinary anthelmintic. Praziquantel is FDA approved in the US for the treatment of schistosomiasis and liver flukes, although it is effective in other infections. [37]
This is a particularly serious problem in helminth parasites of small ruminant farm animals. [12] There are many factors that contribute to anthelmintic resistance, such as frequent, mass anthelmintic treatment, underdosing, treating repeatedly with only one anthelmintic, and resistance being transmitted during transfer of animals. [12]
This therapy ties to the Hygiene hypothesis in that the lack of exposure to bacteria and parasites such as helminths can cause a weaker immune system leading to being more susceptible to autoimmune disease. [4] [5] Helminth worms are members of two phyla: nematodes, which are primarily used in human helminthic therapy, and flat worms . [2]
Major groups of parasites include protozoans (organisms having only one cell) and parasitic worms (helminths). Of these, protozoans, including cryptosporidium, microsporidia, and isospora, are most common in HIV-infected persons. Each of these parasites can infect the digestive tract, and sometimes two or more can cause infection at the same time.
Helminth proteins can result in a deregulated response to infection, and are implicated in reduced reactivity to other antigens. [1] Other helminth proteins promote parasite survival in other ways, particularly since parasites must depend on hosts for the supply of essential nutrients. [ 2 ]