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The Belgian Draft Horse is one breed in which JEB occurs Junctional epidermolysis bullosa ( JEB ) is an inherited disorder that is also known as red foot disease or hairless foal syndrome . [ 1 ] JEB is the result of a genetic mutation that inhibits protein production that is essential for skin adhesion. [ 2 ]
Horses that develop purpura haemorrhagica usually have a recent history of strangles (infection with Streptococcus equi subsp. equi) or vaccination (intramuscular or intranasal) for strangles. It is thought to be caused by an auto-immune reaction where antibodies against the S. equi M- or R-protein cross-react with proteins on endothelial cells .
An equine behaviourist said warning signs included ‘pinned ears, tense facial muscles, swishing tails or shifting weight’. An equine behaviourist said warning signs included ‘pinned ears ...
Borna disease, also known as sad horse disease, [1] is an infectious neurological syndrome [2] of warm-blooded animals, caused by Borna disease viruses 1 and 2 (BoDV-1/2). BoDV-1/2 are neurotropic viruses of the species Mammalian 1 orthobornavirus, and members of the Bornaviridae family within the Mononegavirales order.
Horses that only carry one copy of the gene may pass it on to their offspring, but themselves are perfectly healthy—without symptoms of the disease. Because it is recessive, the allele for cerebellar abiotrophy may pass through multiple generations before it is expressed.
Strangles (also called equine distemper) is a contagious upper respiratory tract infection of horses and other equines caused by a Gram-positive bacterium, Streptococcus equi. [1] As a result, the lymph nodes swell, compressing the pharynx , larynx , and trachea , and can cause airway obstruction leading to death, hence the name strangles. [ 2 ]
Horses heterozygous for the Ile118Lys mutation on the equine EDNRB gene—carriers of lethal white syndrome—usually exhibit a white-spotting pattern called "frame", or "frame overo". [5] [7] [9] [13] Frame is characterized by jagged, sharply defined, horizontally oriented white patches that run along the horse's neck, shoulder, flank, and ...
Initial signs include thickening, crusting and folding of the skin. [7] These early signs may be hidden by the long hair ( feather ) on the horse's lower legs. [ 6 ] Affected areas are itchy, causing the horse to stamp its feet and rub its legs, and painful, so that the horse may be reluctant to allow its legs to be touched. [ 4 ]