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  2. Timeline of peptic ulcer disease and Helicobacter pylori

    en.wikipedia.org/wiki/Timeline_of_peptic_ulcer...

    The European Helicobacter Pylori Study Group published the Maastricht 2-2000 Consensus Report, suggesting a "test-and-treat" strategy for H. pylori in young patients without atypical symptoms. This strategy advocates the use of noninvasive testing to evaluate for H. pylori and simply treating if found, even in the absence of ulcer disease ...

  3. Helicobacter pylori - Wikipedia

    en.wikipedia.org/wiki/Helicobacter_pylori

    Helicobacter pylori, previously known as Campylobacter pylori, is a gram-negative, flagellated, helical bacterium. Mutants can have a rod or curved rod shape that exhibits less virulence . [ 1 ] [ 2 ] Its helical body (from which the genus name Helicobacter derives) is thought to have evolved to penetrate the mucous lining of the stomach ...

  4. Barry Marshall - Wikipedia

    en.wikipedia.org/wiki/Barry_Marshall

    Marshall did not develop antibodies to H. pylori, suggesting that innate immunity can sometimes eradicate acute H. pylori infection. Marshall's illness and recovery, based on a culture of organisms extracted from a patient, fulfilled Koch's postulates for H. pylori and gastritis, but not for peptic ulcers.

  5. Peptic ulcer disease - Wikipedia

    en.wikipedia.org/wiki/Peptic_ulcer_disease

    Helicobacter pylori is one of the major causative factors of peptic ulcer disease. It secretes urease to create an alkaline environment, which is suitable for its survival. It expresses blood group antigen-binding adhesin (BabA) and outer inflammatory protein adhesin (OipA), which enables it to attach to the gastric epithelium.

  6. Helicobacter heilmannii s.s - Wikipedia

    en.wikipedia.org/wiki/Helicobacter_heilmannii_s.s

    Helicobacter heilmannii s.s. (H. heilmannii s.s.) is a species within the Helicobacter genus of Gram negative bacteria. [1] Helicobacter pylori (H. pylori) is by far the best known Helicobacter species primarily because humans infected with it may develop gastrointestinal tract diseases such as stomach inflammation, stomach ulcers, duodenal ulcers, stomach cancers of the non-lymphoma type, and ...

  7. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    PPIs have been used successfully in triple-therapy regiments with clarithromycin and amoxicillin for the eradication of Helicobacter pylori with no significant difference between different PPI-based regimens. [10] General structure of proton pump inhibitors. Asterisk indicates stereocenter. Dots indicate lone pair

  8. Helicobacter pylori eradication protocols - Wikipedia

    en.wikipedia.org/wiki/Helicobacter_pylori...

    The success of H. pylori cure depends on the type and duration of therapy, patient compliance and bacterial factors such as antibiotic resistance. Patients most often fail to respond to initial H. pylori eradication therapy because of noncompliance or antibiotic resistance. Patients should be queried about any side effects, missed doses, and ...

  9. John Lykoudis - Wikipedia

    en.wikipedia.org/wiki/John_Lykoudis

    John Lykoudis (Greek: Ιωάννης Λυκούδης; 1910 in Missolonghi – 1980) was a Greek physician and politician. He treated patients who had peptic ulcer disease with antibiotics long before it was commonly recognized that bacteria were a dominant cause for the disease. [1]