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Cervical effacement: 0-30% 40-50% 60-70% 80+% Effacement translates to how 'thin' the cervix is. The cervix is normally approximately three centimetres long, as it prepares for labour and labour continues the cervix will efface until it is 'fully effaced' (paper-thin). Cervical dilation: Closed 1–2 cm 3–4 cm 5+cm
Cervical effacement is an important component of the Bishop score and is reported as a percentage. 0% indicates the cervix is at normal length, 50% indicates the cervix is half of the expected length and 100% effaced means the cervix is paper thin. [10] The Bishop score has been modified in current medical practice.
Cervical cancer is a type of gynecological cancer that begins from cells lining the cervix, the lower part of the uterus. [14] Cervical cancer begins when the cells that line the cervix become abnormal and grow in a pattern that is atypical for non-cancerous cells. [14] Cervical cancer is typically first identified with an abnormal pap smear. [14]
3D medical illustration depicting the TNM stages in breast cancer. Cancer staging can be divided into a clinical stage and a pathologic stage. In the TNM (Tumor, Node, Metastasis) system, clinical stage and pathologic stage are denoted by a small "c" or "p" before the stage (e.g., cT3N1M0 or pT2N0).
Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.
[3] [26] It is the second-most common cause of female-specific cancer after breast cancer, accounting for around 8% of both total cancer cases and total cancer deaths in women. [ 27 ] 88% (2020 figure) of cervical cancers and 90% of deaths occur in low- and middle-income countries (LMICs) and 2% (2020 figure) in high-income countries (HICs) .
Normal cervical mucosa contains glycogen and stains brown, whereas abnormal areas, such as early cervical cancer, do not take up the stain. The abnormal areas can then be biopsied and examined histologically. The composition of Schiller's iodine is the same as Lugol's iodine, the latter being more concentrated.
The Bethesda system (TBS), officially called The Bethesda System for Reporting Cervical Cytology, is a system for reporting cervical or vaginal cytologic diagnoses, [1] used for reporting Pap smear results. It was introduced in 1988 [2] and revised in 1991, [3] 2001, [1] [4] [5] and 2014. [6]