Search results
Results from the WOW.Com Content Network
The World Association of Sarcoidosis and other Granulomatous Disorders, also known as WASOG is an organisation of physicians involved in the diagnosis and treatment of sarcoidosis and related conditions.
Infliximab is a chimeric monoclonal antibody biologic. It seems to work by binding to and neutralizing TNF-α, preventing it from interacting with its receptors on the cell. [23] TNF-α is a chemical messenger and a key part of the autoimmune reaction. Infliximab was originally developed in mice as a mouse antibody.
The anti-TNF-α monoclonal antibody infliximab is a major biological therapy for inflammatory bowel disease. Biological therapy, the use of medications called biopharmaceuticals or biologics that are tailored to specifically target an immune or genetic mediator of disease, plays a major role in the treatment of inflammatory bowel disease. [1]
Likewise chlorambucil and cyclophosphamide are seldom used in the treatment of sarcoidosis due to their high degree of toxicity, especially their potential for causing malignancies. [127] Infliximab has been used successfully to treat pulmonary sarcoidosis in clinical trials in a number of cases. [116]
Therapeutic, diagnostic and preventive monoclonal antibodies are clones of a single parent cell. When used as drugs, the International Nonproprietary Names (INNs) end in -mab.
It was considered a first-aid treatment rather than a cure and aimed to control inflammation. [2] It was thought that the reduction in pain and swelling that occurred as a result of decreased inflammation helped with healing. [1] The protocol was often used to treat sprains, strains, cuts, bruises, and other similar injuries. [3]
Only 1 percent of people with sarcoidosis will have neurosarcoidosis alone without involvement of any other organs. Diagnosis can be difficult, with no test apart from biopsy achieving a high accuracy rate. Treatment is with immunosuppression. [1] The first case of sarcoidosis involving the nervous system was reported in 1905. [2] [3]
In medicine, infusion therapy deals with all aspects of fluid and medication infusion, via intravenous or subcutaneous application. A special infusion pump can be used for this purpose. [1] A fenestrated catheter is frequently inserted into the localized area to be treated. There are a range of delivery methods for infusion of drugs via catheter: