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  2. Calcifediol - Wikipedia

    en.wikipedia.org/wiki/Calcifediol

    In medical practice, a blood test for 25-hydroxy-vitamin D, 25(OH)D, is used to determine an individual's vitamin D status. [11] The name 25(OH)D refers to any combination of calcifediol (25-hydroxy-cholecalciferol), derived from vitamin D 3, and ercalcidiol (25-hydroxy-ergocalciferol), [1] derived from vitamin D 2. The first of these (also ...

  3. Vitamin D - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D

    While some studies have found that vitamin D 3 raises 25(OH)D blood levels faster and remains active in the body longer, [44] [45] others contend that vitamin D 2 sources are equally bioavailable and effective for raising and sustaining 25(OH)D. [46] [47] If digestive disorders compromise absorption, then intramuscular injection of up to ...

  4. Vitamin D deficiency - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D_deficiency

    Serum level of 25(OH)D is the laboratory test ordered to indicate whether or not a person has vitamin D deficiency or insufficiency. [53] It is also considered reasonable to treat at-risk persons with vitamin D supplementation without checking the level of 25(OH)D in the serum, as vitamin D toxicity has only been rarely reported to occur. [53]

  5. 25-Hydroxyvitamin D 1-alpha-hydroxylase - Wikipedia

    en.wikipedia.org/wiki/25-Hydroxyvitamin_D_1...

    25-Hydroxyvitamin D 1-alpha-hydroxylase (VD 1A hydroxylase) also known as calcidiol 1-monooxygenase [5] or cytochrome p450 27B1 (CYP27B1) or simply 1-alpha-hydroxylase is a cytochrome P450 enzyme that in humans is encoded by the CYP27B1 gene. [6] [7] [8]

  6. Vitamin D toxicity - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D_toxicity

    Vitamin D toxicity, or hypervitaminosis D, is the toxic state of an excess of vitamin D.The normal range for blood concentration of 25-hydroxyvitamin D in adults is 20 to 50 nanograms per milliliter (ng/mL).

  7. Calcitriol - Wikipedia

    en.wikipedia.org/wiki/Calcitriol

    Calcitriol is, strictly, the 1-hydroxylation product of calcifediol (25-OH vitamin D 3), derived from cholecalciferol (vitamin D 3), rather than the product of hydroxylations of ergocalciferol (vitamin D 2). [6] 1α,25-Dihydroxyergocalciferol (ercalcitriol) should be used for the vitamin D 2 product. [6] However, the terminology of 1,25 ...

  8. 24,25-Dihydroxycholecalciferol - Wikipedia

    en.wikipedia.org/wiki/24,25-Dihydroxycholecalciferol

    24,25-dihydroxyvitamin D 3 is formed from 25-hydroxyvitamin D 3 by the action of CYP24A1 (25-hydroxyvitamin D3-24-hydroxylase). CYP24A1 appears to be "a multicatalytic enzyme catalyzing most, if not all, of the reactions in the C-24/C-23 pathway of 25-OH-D 3 metabolism." [5]

  9. CYP2R1 - Wikipedia

    en.wikipedia.org/wiki/CYP2R1

    The conversion of vitamin D, especially cholecalciferol, to 25(OH)D (calcifediol) is one of the key steps in the vitamin D hormonal system. The CYP2R1 enzymatic activity achieving this process was previously thought to be constitutively expressed and stable, so that serum 25(OH)D was a measure of the supply of vitamin D. [9]

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