Search results
Results from the WOW.Com Content Network
Targeted alpha-particle therapy (or TAT) is an in-development method of targeted radionuclide therapy of various cancers. It employs radioactive substances which undergo alpha decay to treat diseased tissue at close proximity. [1] It has the potential to provide highly targeted treatment, especially to microscopic tumour cells.
Alpha radiation is a nuclear phenomenon in which a heavy radionuclide emits an energetic alpha particle (consisting of two protons and two neutrons) and transmutes to a different radionuclide. The emitted alpha particle has a range in tissue of only 40-90 microns, which minimizes collateral damage when used for treatment purposes.
Alpha particles, also called alpha rays or alpha radiation, consist of two protons and two neutrons bound together into a particle identical to a helium-4 nucleus. [5] They are generally produced in the process of alpha decay but may also be produced in different ways. Alpha particles are named after the first letter in the Greek alphabet, α.
The required decisions include how many radiation beams to use, which angles each will be delivered from, whether attenuating wedges be used, and which MLC configuration will be used to shape the radiation from each beam. Once the treatment planner has made an initial plan, the treatment planning system calculates the required monitor units to ...
Stereotactic radiation is a specialized type of external beam radiation therapy. It uses focused radiation beams targeting a well-defined tumor using extremely detailed imaging scans. Radiation oncologists perform stereotactic treatments, often with the help of a neurosurgeon for tumors in the brain or spine.
Americium-241, an alpha emitter, is used in smoke detectors. The alpha particles ionize air in an open ion chamber and a small current flows through the ionized air. Smoke particles from the fire that enter the chamber reduce the current, triggering the smoke detector's alarm. Radium-223 is also an alpha emitter. It is used in the treatment of ...
The types R of ionizing radiation most considered in RBE evaluation are X-rays and gamma radiation (both consisting of photons), alpha radiations (helium-4 nuclei), beta radiation (electrons and positrons), neutron radiation, and heavy nuclei, including the fragments of nuclear fission. For some kinds of radiation, the RBE is strongly dependent ...
Alpha radiation has a very short range in tissues compared to beta or gamma radiation: around 2–10 cells. This reduces damage to surrounding healthy tissues, producing an even more localized effect than the beta-emitter strontium-89, also used to treat bone cancer. [17] Taking account of its preferential uptake by bone and the alpha particles ...