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  2. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    Formulations are 500/1, 500/2, 500/4, 1000/2, and 1000 mg/4 mg of metformin/rosiglitazone. In 2009, it was the most popular metformin combination. [183] In 2005, the stock of Avandamet was removed from the market, after inspections showed the factory where it was produced was violating good manufacturing practices. [184]

  3. Protein pKa calculations - Wikipedia

    en.wikipedia.org/wiki/Protein_pKa_calculations

    From the titration of protonatable group, one can read the so-called pK a 1 ⁄ 2 which is equal to the pH value where the group is half-protonated (i.e. when 50% such groups would be protonated). The pK a 1 ⁄ 2 is equal to the Henderson–Hasselbalch pK a (pK HH a) if the titration curve follows the Henderson–Hasselbalch equation. [14]

  4. Henderson–Hasselbalch equation - Wikipedia

    en.wikipedia.org/wiki/Henderson–Hasselbalch...

    The Henderson–Hasselbalch equation relates the pH of a solution containing a mixture of the two components to the acid dissociation constant, K a of the acid, and the concentrations of the species in solution. [6] Simulated titration of an acidified solution of a weak acid (pK a = 4.7) with alkali

  5. pH - Wikipedia

    en.wikipedia.org/wiki/PH

    At 25 °C (77 °F), solutions with a pH less than 7 are acidic, and solutions with a pH greater than 7 are basic. Solutions with a pH of 7 at 25 °C are neutral (i.e. have the same concentration of H + ions as OH − ions, i.e. the same as pure water). The neutral value of the pH depends on the temperature and is lower than 7 if the temperature ...

  6. When Is the Best Time to Take Metformin? - AOL

    www.aol.com/best-time-metformin-141700387.html

    There’s no best time to take metformin for weight loss or type 2 diabetes (or any other condition). But taking it at the same time each day can help you stay consistent and avoid missing or ...

  7. Metformin Can Help You Lose Weight Loss, But It Also Has ...

    www.aol.com/metformin-help-lose-weight-loss...

    Another small study on people without diabetes who were overweight or had obesity found that those taking metformin lost between 5.6 and 6.5 percent of their body weight. In contrast, the control ...

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