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Crossword-like puzzles, for example Double Diamond Puzzles, appeared in the magazine St. Nicholas, published since 1873. [32] Another crossword puzzle appeared on September 14, 1890, in the Italian magazine Il Secolo Illustrato della Domenica. It was designed by Giuseppe Airoldi and titled "Per passare il tempo" ("To pass the time"). Airoldi's ...
The puzzle proved popular, and Sulzberger himself authored a Times puzzle before the year was out. [11] In 1950, the crossword became a daily feature. That first daily puzzle was published without an author line, and as of 2001 the identity of the author of the first weekday Times crossword remained unknown. [13]
Voltage-gated ion channel. When the membrane is polarized, the voltage sensing domain of the channel shifts, opening the channel to ion flow (ions represented by yellow circles). Voltage-gated ion channels open and close in response to the electrical potential across the cell membrane. Portions of the channel domain act as voltage sensors.
An example is the long-awaited crystal structure of a voltage-gated potassium channel, which was reported in May 2003. [ 40 ] [ 41 ] One inevitable ambiguity about these structures relates to the strong evidence that channels change conformation as they operate (they open and close, for example), such that the structure in the crystal could ...
A 15x15 lattice-style grid is common for cryptic crosswords. A cryptic crossword is a crossword puzzle in which each clue is a word puzzle. Cryptic crosswords are particularly popular in the United Kingdom, where they originated, [1] as well as Ireland, the Netherlands, and in several Commonwealth nations, including Australia, Canada, India, Kenya, Malta, New Zealand, and South Africa.
The structure of the complex of sodium (Na +) and the antibiotic monensin A Structure of a potassium complex of a crown ether, a synthetic ionophore-ion complex. Biological activities of metal ion-binding compounds can be changed in response to the increment of the metal concentration, and based on the latter compounds can be classified as "metal ionophores", "metal chelators" or "metal ...
Analysis Utility Branch Dose–response curves: Graph that shows the magnitude of the response of an organism, as a function of exposure (or doses) to a stimulus or stressor (usually a chemical) after a certain exposure time [2]
Laboratory methods and techniques, as used in fields like biology, biochemistry, biophysics, chemistry, molecular biology, etc. Wikimedia Commons has media related to Laboratory techniques . Contents