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A calibration curve plot showing limit of detection (LOD), limit of quantification (LOQ), dynamic range, and limit of linearity (LOL).. In analytical chemistry, a calibration curve, also known as a standard curve, is a general method for determining the concentration of a substance in an unknown sample by comparing the unknown to a set of standard samples of known concentration. [1]
The scaled sum of a sequence of i.i.d. random variables with finite positive variance converges in distribution to the normal distribution. In probability theory, the central limit theorem (CLT) states that, under appropriate conditions, the distribution of a normalized version of the sample mean converges to a standard normal distribution.
First, regression analysis is widely used for prediction and forecasting, where its use has substantial overlap with the field of machine learning. Second, in some situations regression analysis can be used to infer causal relationships between the independent and dependent variables.
In statistics, polynomial regression is a form of regression analysis in which the relationship between the independent variable x and the dependent variable y is modeled as an n th degree polynomial in x. Polynomial regression fits a nonlinear relationship between the value of x and the corresponding conditional mean of y, denoted E (y | x).
The following expressions can be used to calculate the upper and lower 95% confidence limits, ... the mean and standard deviation are descriptive statistics, whereas ...
A statistical hypothesis test is a method of statistical inference used to decide whether the data sufficiently supports a particular hypothesis. A statistical hypothesis test typically involves a calculation of a test statistic. Then a decision is made, either by comparing the test statistic to a critical value or equivalently by evaluating a ...
In probability theory and statistics, skewness is a measure of the asymmetry of the probability distribution of a real -valued random variable about its mean. The skewness value can be positive, zero, negative, or undefined. For a unimodal distribution (a distribution with a single peak), negative skew commonly indicates that the tail is on the ...
Sample size determination or estimation is the act of choosing the number of observations or replicates to include in a statistical sample. The sample size is an important feature of any empirical study in which the goal is to make inferences about a population from a sample. In practice, the sample size used in a study is usually determined ...