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The Centor criteria were originally developed for adults. A study published in the British Medical Journal in 2013 looked at whether it could be applied to children aged 2–16. It was a retrospective study (2008–2010) and looked at 441 children who attended a Belgian hospital emergency department and had a throat swab taken.
Strep throat is a common bacterial infection in children. [2] It is the cause of 15–40% of sore throats among children [7] [13] and 5–15% among adults. [8] Cases are more common in late winter and early spring. [13] Potential complications include rheumatic fever and peritonsillar abscess. [1] [2]
Throat swab. Differentiating a viral and a bacterial cause of a sore throat based on symptoms alone is difficult. [29] Thus, a throat swab often is done to rule out a bacterial cause. [30] The modified Centor criteria may be used to determine the management of people with pharyngitis. Based on five clinical criteria, it indicates the ...
The Centor criteria are also ineffective in diagnosis for tonsillitis in children and in secondary care settings (hospitals). [15] A modified version of the Centor criteria, which modified the original Centor criteria in 1998, is often used to aid in diagnosis.
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In a prediction rule study, investigators identify a consecutive group of patients who are suspected of having a specific disease or outcome. The investigators then obtain a standard set of clinical observations on each patient and a test or clinical follow-up to define the true state of the patient.
This is especially true for Healthy life expectancy, the definition of which criteria may change over time, even within a country. For example, Canada is a country with a fairly high overall life expectancy at 81.63 years; however, this number decreases to 75.5 years for Indigenous people in the country. [4]
Over time, affected children experience mental impairment, worsening seizures and progressive loss of sight, speech and motor skills. Batten disease is a terminal disease; life expectancy varies depending on the type or variation. [7] [8] Females with juvenile Batten disease show first symptoms a year later than males, but on average die a year ...