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Picamilon (also known as N-nicotinoyl-GABA, pycamilon, and pikamilon) is a drug formed by a synthetic combination of niacin and γ-aminobutyric acid (GABA). It was developed in the Soviet Union in 1969 [3] and further studied in both Russia [4] and Japan as a prodrug of GABA. [5] In Russia, picamilon is sold as a prescription drug.
There is no direct evidence to prove or disprove that Picamilon acts as a pro-drug. Finally a more important question of whether Picamilon has any pharmacological effect to begin with. Are there any controlled clinical studies proving Picamilon's efficacy? If there is no efficacy, the question of whether Picamilon acts as a pro-drug becomes moot.
This page was last edited on 20 October 2024, at 22:19 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
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Emoxypine (2-ethyl-6-methyl-3-hydroxypyridine), also known as Mexidol or Mexifin, a succinate salt, is chemical compound which is claimed by its manufacturer, the Russian company Pharmasoft Pharmaceuticals, to have antioxidant and actoprotector properties, [2] [3] but these purported properties of emoxypine have not been proven. [4]