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An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer. They may be used for severe cases of gastroenteritis, especially if the patient is dehydrated. [1] [2]
A newer class of drugs known as the NK 1 antagonists are a recently developed class of very efficacious drugs for controlling CINV. These drugs are often used alongside 5HT 3 inhibitors and corticosteroids to form a very potent cocktail of antiemetics that verge on achieving a nearly complete patient response (that is, completely stopping CINV ...
There are few side effects related to the use of 5-HT 3 antagonists; the most common are constipation or diarrhea, headache, and dizziness. [28] Unlike antihistamines with antiemetic properties such as cyclizine, 5-HT 3 antagonists do not produce sedation, nor do they cause extrapyramidal effects, as phenothiazines (such as prochlorperazine ...
Often times, a short-term antiemetic — or anti-vomit medication — may help during the initial few doses." ... Because semaglutide medications have been linked to side effects like nausea ...
In 2001, the FDA changed the labeling requirements for droperidol injection to include a Black Box Warning, citing concerns of QT prolongation and torsades de pointes.The evidence for this is disputed, with 9 reported cases of torsades in 30 years and all of those having received doses in excess of 5 mg. [9] QT prolongation is a dose-related effect, [10] and it appears that droperidol is not a ...
The US Food and Drug Administration (FDA) has expressed concerns about serious adverse side effects and concerns about its effectiveness. [34] The FDA identified serious cardiac adverse events associated with domperidone use in lactating individuals, including arrhythmias, cardiac arrest, and sudden death.
This D 2 blockade results in antipsychotic, antiemetic and other effects. Hyperprolactinemia is a side effect of dopamine antagonists as blockade of D 2 receptors within the tuberoinfundibular pathway results in increased plasma levels of prolactin due to increased secretion by lactotrophs in the anterior pituitary.
AHFS/Drugs.com: Monograph: MedlinePlus: a682693: ... Tigan) is an antiemetic used to prevent nausea and vomiting. Mechanism of action ... Possible side effects ...