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The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol under the brand names Diane or Diane-35 among others, is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender individuals ...
The pharmacology of cyproterone acetate (CPA) concerns the pharmacology (pharmacodynamics, pharmacokinetics, and routes of administration) of the steroidal antiandrogen and progestin medication cyproterone acetate. CPA blocks the effects of androgens like testosterone in the body, which it does by preventing them from interacting with their ...
[1] [2] [3] It is a precursor of cyproterone acetate (CPA), an antiandrogen, progestin, and antigonadotropin which was introduced instead of cyproterone and is widely used as a medication. [1] [2] Cyproterone and CPA were among the first antiandrogens to be developed. [4] The term cyproterone is often used as a synonym and shorthand for ...
Unlike antigonadotropic antiandrogens like cyproterone acetate and GnRH analogues, bicalutamide does not suppress production of testosterone or estradiol and instead actually increases it [citation needed], which has an important involvement in the differential side-effect profiles of the medications. [citation needed]
[4] [19] Both EE and CPA have antigonadotropic effects and act as contraceptives in women by suppressing ovulation. [17] The antigonadotropic effects of EE and CPA also contribute to the antiandrogenic efficacy of the medication by suppressing androgen production by the ovaries. [18]
But some research has noted rare but serious side effects of once-weekly, 2.4-milligram (mg) semaglutide injections, such as pancreatitis, acute kidney injury, gallbladder issues, and thyroid cancer.
Side effects of cyproterone acetate; Template:Side effects of cyproterone acetate in the SExual-HOrmonal Surveillance STudy (SEHOST) Template:Side effects of estradiol undecylate versus cyproterone acetate in men; Template:Side effects of estrogen plus high- versus low-dose cyproterone acetate in women
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