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Normal pressure range (in mmHg) [5] Central venous pressure: 3–8 Right ventricular pressure: systolic: 15–30 diastolic: 3–8 Pulmonary artery pressure: systolic: 15–30 diastolic: 4–12 Pulmonary vein/ Pulmonary capillary wedge pressure. 2–15 Left ventricular pressure: systolic: 100–140 diastolic: 3–12
Portal hypertension is defined as increased portal venous pressure, with a hepatic venous pressure gradient greater than 5 mmHg. [3] [4] Normal portal pressure is 1–4 mmHg; clinically insignificant portal hypertension is present at portal pressures 5–9 mmHg; clinically significant portal hypertension is present at portal pressures greater than 10 mmHg. [5]
As the pulmonary venous pressure rises, these pressures overwhelm the barriers and fluid enters the alveoli when the pressure is above 25 mmHg. [14] Depending on whether the cause is acute or chronic determines how fast pulmonary edema develops and the severity of symptoms. [ 12 ]
Chronic venous insufficiency (CVI) is a medical condition characterized by blood pooling in the veins, leading to increased pressure and strain on the vein walls. [1] The most common cause of CVI is superficial venous reflux, which often results in the formation of varicose veins , a treatable condition. [ 2 ]
Pulmonary hypertension is defined as a mean PAP of at least 20 mm Hg (3300 Pa) at rest, and PAH is defined as precapillary pulmonary hypertension (i.e. mean PAP ≥ 20 mm Hg with pulmonary arterial occlusion pressure [PAOP] ≤ 15 mm Hg and pulmonary vascular resistance [PVR] > 3 Wood Units). [58]
The assumption that a low mixed venous oxygen saturation (normal = 60% except for the coronary sinus where it approximates 40% reflecting the high metabolic rate of the myocardium) represents less than adequate oxygen delivery is consistent with physiological and metabolic observations. [10]
Currently, there are three recognised targeted treatment options available including the standard treatment of pulmonary endarterectomy (PEA). Balloon pulmonary angioplasty (BPA) and pulmonary vasodilator drug treatment may be considered for those people that are not suitable for surgery. [11]
The horizontal axis of Guyton diagram represents right atrial pressure or central venous pressure, and the vertical axis represents cardiac output or venous return. The red curve sloping upward to the right is the cardiac output curve, and the blue curve sloping downward to the right is the venous return curve. A steady state is formed at the ...