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Lead in the bones, teeth, hair, and nails is bound tightly and not available to other tissues, and is generally thought not to be harmful. [180] In adults, 94% of absorbed lead is deposited in the bones and teeth, but children only store 70% in this manner, a fact which may partially account for the more serious health effects on children. [ 26 ]
However hair-loss generally occurs only with low doses; with high doses the thallium kills before hair loss can occur. [6] Thallium was an effective murder weapon before its effects became understood and an antidote (Prussian blue) was discovered. [7] Thallium is often imported for products like optical lenses and electronics.
Frictional alopecia is the loss of hair that is caused by rubbing of the hair, follicles, or skin around the follicle. [1] The most typical example of this is the loss of ankle hair among people who wear socks constantly for years. [2] The hair may not grow back even years after the source of friction has ended.
People who get erethism are often exposed to mercury through their jobs. Some of the higher risk jobs that can lead to occupational exposure of workers to mercury are working in a chlor-alkali , thermometer , glassblowing , or fluorescent light bulb factory, and working in construction , dental clinics , or in gold and silver mines .
In cases with a greater number of patches, hair can either grow back or progress to alopecia areata totalis or, in rare cases, alopecia areata universalis. [ 21 ] No loss of body function occurs, and the effects of alopecia areata are psychological (loss of self-image due to hair loss), although these can be severe.
The researchers also learned that using a curling iron or a flat iron and applying high heat to hair that has been treated with these products can intensify the release of these chemicals.
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They found the gene P2RY5 causes a rare, inherited form of hair loss called hypotrichosis simplex. It is the first receptor in humans known to play a role in hair growth. [ 103 ] [ 104 ] [ 105 ] Researchers found that disruption of the gene SOX21 in mice caused cyclical hair loss.