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2. Acid-fastness - Wikipedia

   en.wikipedia.org/wiki/Acid-fastness

   [1] [2] Once stained as part of a sample, these organisms can resist the acid and/or ethanol-based decolorization procedures common in many staining protocols, hence the name acid-fast. [2] The mechanisms of acid-fastness vary by species although the most well-known example is in the genus Mycobacterium, which includes the species responsible ...

3. Mycobacterium leprae - Wikipedia

   en.wikipedia.org/wiki/Mycobacterium_leprae

   Mycobacterium leprae is an intracellular, pleomorphic, non-sporing, non-motile, acid-fast, pathogenic bacterium. [3] It is an aerobic bacillus (rod-shaped bacterium) with parallel sides and round ends, surrounded by the characteristic waxy coating of mycolic acid unique to mycobacteria.

4. Mycobacterium tuberculosis - Wikipedia

   en.wikipedia.org/wiki/Mycobacterium_tuberculosis

   However, the mycolic acid in the cell wall of M. tuberculosis does not absorb the stain. Instead, acid-fast stains such as Ziehl–Neelsen stain, or fluorescent stains such as auramine are used. [4] Cells are curved rod-shaped and are often seen wrapped together, due to the presence of fatty acids in the cell wall that stick together. [11]

5. Mycobacterium - Wikipedia

   en.wikipedia.org/wiki/Mycobacterium

   The two most common methods for visualizing these acid-fast bacilli as bright red against a blue background are the Ziehl-Neelsen stain and modified Kinyoun stain. Fite's stain is used to color M. leprae cells as pink against a blue background. Rapid Modified Auramine O Fluorescent staining has specific binding to slowly-growing mycobacteria ...

6. Leprosy - Wikipedia

   en.wikipedia.org/wiki/Leprosy

   The diagnosis is confirmed by finding acid-fast bacilli in a biopsy of the skin. [3] Leprosy is curable with multidrug therapy. [4] Treatment of paucibacillary leprosy is with the medications dapsone, rifampicin, and clofazimine for six months. [9] Treatment for multibacillary leprosy uses the same medications for 12 months. [9]

7. Mycobacterium phlei - Wikipedia

   en.wikipedia.org/wiki/Mycobacterium_phlei

   Mycobacterium phlei is a species of acid-fast bacteria in the genus Mycobacterium. [1] It is characterized as one of the fast-growing mycobacteria. M. phlei has only occasionally been isolated in human infections, and patients infected with M. phlei generally respond well to anti-mycobacterial therapy. M. phlei has an unusually high GC-content ...

8. Ziehl–Neelsen stain - Wikipedia

   en.wikipedia.org/wiki/Ziehl–Neelsen_stain

   The acid-fast staining method, in conjunction with auramine phenol staining, serves as the standard diagnostic tool and is widely accessible for rapidly diagnosing tuberculosis (caused by Mycobacterium tuberculosis) and other diseases caused by atypical mycobacteria, such as leprosy (caused by Mycobacterium leprae) and Mycobacterium avium ...

9. Kinyoun stain - Wikipedia

   en.wikipedia.org/wiki/Kinyoun_stain

   The Kinyoun method can be modified as a weak acid fast stain, which uses 0.5–1.0% sulfuric acid instead of hydrochloric acid.The weak acid fast stain, in addition to staining Mycobacteria, will also stain organisms that are not able to maintain the carbol fuchsin after decolorizing with HCl, such as Nocardia species and Cryptosporidium.