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Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). [ 2 ] [ 3 ] Most people are infected by the virus as children, when the disease produces few or no symptoms. [ 2 ]
This photomicrograph depicts leukemia cells that contain Epstein–Barr virus using a FA staining technique. Epstein–Barr virus, EBV, is a member of the Herpesvirus family, and is one of the most common human viruses. When infection with EBV occurs during adolescence or young adulthood, it causes infectious mononucleosis 35% to 50% of the time.
The Epstein–Barr virus (EBV) is one of the nine known human herpesvirus types in the herpes family, and is one of the most common viruses in humans. EBV is a double-stranded DNA virus and is also called human herpesvirus 4 (HHV-4). [2] Epstein–Barr virus (EBV) is the first identified oncogenic virus, or a virus that can cause cancer. EBV ...
The mononuclear spot test or monospot test, a form of the heterophile antibody test, [1] is a rapid test for infectious mononucleosis due to Epstein–Barr virus (EBV). It is an improvement on the Paul–Bunnell test. [2] The test is specific for heterophile antibodies produced by the human immune system in response to EBV
[1] [2] The virus establishes latent infection and causes infectious mononucleosis. There is also increasingly more evidence that EBV may be a trigger of multiple sclerosis . [ 3 ] It is a dual- tropic virus, meaning that it infects two different host cell types — in this case, both B cells and epithelial cells .
Doing the same motion repeatedly can cause muscles, ligaments, and tendons to become swollen and inflamed, which causes the ache. In addition to aches, you may notice a lack of strength and ...
In immunocompetent patients, Epstein-Barr virus can cause infectious mononucleosis in adolescents, which is otherwise asymptomatic in children during their childhood. However, in immunosuppressed transplant patients, the lack of T-cell immunosurveillance can lead to the proliferation of these EBV-infected B-lymphocytes. [citation needed]
Gammaherpesviruses are of primary interest due to the two human viruses, EBV (Epstein–Barr virus) and KSHV (Kaposi's sarcoma-associated herpesvirus) and the diseases they cause. The gammaherpesviruses replicate and persist in lymphoid cells but some are capable of undergoing lytic replication in epithelial or fibroblast cells.