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This is called a D-zone test, or D test. If a 'D' shape is formed around the clindamycin disk (distinguished from a circular zone of inhibition) then the isolate is reported as resistant to clindamycin. [5] This occurs due to erythromycin inducing the bacteria's erm gene, and thus making it resistant to clindamycin (MLS-B phenotype). [6] [7]
In clinical medicine, antibiotics are most frequently prescribed on the basis of a person's symptoms and medical guidelines. This method of antibiotic selection is called empiric therapy, [1] and it is based on knowledge about what bacteria cause an infection, and to what antibiotics bacteria may be sensitive or resistant. [1]
The disk diffusion test (also known as the agar diffusion test, Kirby–Bauer test, disc-diffusion antibiotic susceptibility test, disc-diffusion antibiotic sensitivity test and KB test) is a culture-based microbiology assay used in diagnostic and drug discovery laboratories. In diagnostic labs, the assay is used to determine the susceptibility ...
It was a retrospective study (2008–2010) and looked at 441 children who attended a Belgian hospital emergency department and had a throat swab taken. It concluded that the Centor criteria are ineffective in predicting the presence of Group A beta-haemolytic streptococcus (i.e. antibiotic treatment-worthy) on throat swab cultures in children. [4]
Erythromycin is an antibiotic used for the treatment of a number of bacterial infections. [1] This includes respiratory tract infections , skin infections , chlamydia infections , pelvic inflammatory disease , and syphilis . [ 1 ]
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The selection and use of essential medicines. Twentieth report of the WHO Expert Committee 2015 (including 19th WHO Model List of Essential Medicines and 5th WHO Model List of Essential Medicines for Children). Geneva: World Health Organization. hdl: 10665/189763. ISBN 9789240694941. ISSN 0512-3054. WHO technical report series; no. 994.
Agar dilution is one of two methods (along with broth dilution) used by researchers to determine the minimum inhibitory concentration (MIC) of antibiotics. It is the dilution method most frequently used to test the effectiveness of new antibiotics when a few antibiotics are tested against a large panel of different bacteria.