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  2. Ankle fusion - Wikipedia

    en.wikipedia.org/wiki/Ankle_fusion

    Ankle fusion is considered to be the gold standard for treatment of end-stage ankle arthritis. [1] It trades joint mobility for relief from pain. Ankle fusion has also been used to resolve foot drop in certain circumstances. [2] [3] Complications of ankle fusion may include infection, non-union, and, rarely, amputation. [1]

  3. Nelson's syndrome - Wikipedia

    en.wikipedia.org/wiki/Nelson's_syndrome

    Nelson's syndrome is a disorder that occurs in about one in four patients who have had both adrenal glands removed to treat Cushing's disease. [1] In patients with pre-existing adrenocorticotropic hormone ()-secreting pituitary adenomas, loss of adrenal feedback following bilateral adrenalectomy can trigger the rapid growth of the tumor, leading to visual symptoms (e.g. bitemporal hemianopsia ...

  4. Endoscopic endonasal surgery - Wikipedia

    en.wikipedia.org/wiki/Endoscopic_endonasal_surgery

    An endocrinologist is only involved in preparation for an endoscopic endonasal surgery, if the tumor is located on the pituitary gland. The tumor is first treated pharmacologically in two ways: controlling the levels of hormones that the pituitary gland secretes and reducing the size of the tumor. If this approach does not work, the patient is ...

  5. Ankle replacement - Wikipedia

    en.wikipedia.org/wiki/Ankle_replacement

    Ankle replacement, or ankle arthroplasty, is a surgical procedure to replace the damaged articular surfaces of the human ankle joint with prosthetic components. This procedure is becoming the treatment of choice for patients requiring arthroplasty, replacing the conventional use of arthrodesis , i.e. fusion of the bones.

  6. Sheehan's syndrome - Wikipedia

    en.wikipedia.org/wiki/Sheehan's_syndrome

    Other hormone-secreting cells of the pituitary undergo rapid growth in pregnant women as well, which contribute to the gland's enlargement. [10] The anterior pituitary is supplied by a low pressure portal venous system. [15] The anterior pituitary is more commonly affected in Sheehan's syndrome because of the structure of the portal venous system.

  7. Syndrome of inappropriate antidiuretic hormone secretion

    en.wikipedia.org/wiki/Syndrome_of_inappropriate...

    Syndrome of inappropriate antidiuretic hormone secretion (SIADH), also known as the syndrome of inappropriate antidiuresis (SIAD), [2] is characterized by a physiologically inappropriate release of antidiuretic hormone (ADH) either from the posterior pituitary gland, or an ectopic non-pituitary source, such as an ADH-secreting tumor in the lung. [1]

  8. AstraZeneca bets on new cancer treatments with $2 billion ...

    www.aol.com/news/astrazeneca-bets-cancer...

    The drugmaker will pay $21 per Fusion share, a premium of more than 97% to the U.S.-listed company's closing price on Monday. ... "Between 30 and 50% of patients with cancer today receive ...

  9. Pituitary adenoma - Wikipedia

    en.wikipedia.org/wiki/Pituitary_adenoma

    Pituitary adenomas are tumors that occur in the pituitary gland. Most pituitary tumors are benign, approximately 35% are invasive and just 0.1% to 0.2% are carcinomas. [1] Pituitary adenomas represent from 10% to 25% of all intracranial neoplasms, with an estimated prevalence rate in the general population of approximately 17%. [1] [2]