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A dermatofibroma, or benign fibrous histiocytomas, is a benign nodule in the skin, typically on the legs, elbows or chest of an adult. [3] It is usually painless. [3] It usually ranges from 0.2cm to 2cm in size but larger examples have been reported. [3] It typically results from mild trauma such as an insect bite. [3]
The hard fibroma (fibroma durum) consists of many fibres and few cells, e.g. in skin it is called dermatofibroma (fibroma simplex or nodulus cutaneous). [2] A special form is the keloid, which derives from hyperplastic growth of scars.
A defect is created surgically (either following removal of a tumor or following cleansing of a wound) An incision is made over the area from where the flap will be taken. The flap is dissected and freed from the surrounding tissue. At least one vein and one artery (which constitutes the vascular pedicle) are dissected.
Removal, if desired or warranted, can be done by a dermatologist, a general practitioner, or a similarly trained professional who may use cauterization, cryosurgery, excision, laser, or surgical ligation to remove the acrochorda. [2] [10] Varied home remedies are unsupported by medical evidence. [10]
Dermatofibroma (benign fibrous histiocytoma, dermal dendrocytoma, fibrous dermatofibroma, fibrous histiocytoma, fibroma simplex, histiocytoma, nodular subepidermal fibrosis, sclerosing hemangioma) Dermatofibrosarcoma protuberans
Various studies find that DFSP-FS tumors have higher rates of recurrence after surgical removal than DFSP tumors and may metastasize (i.e. spread to distant tissues). [2] [8] [9] [10] The tumor cells in DFSP and DFSP-FS harbor one or more fusion gene mutations, i.e. mutations that merge two previously independent genes.
The World Health Organization in 2020 classified the fibro sarcomatous DFSP (DFSP-FS) variant (also termed dermatofibrosarcoma protuberans, fibro sarcomatous) of the dermatofibrosarcoma protuberans as a specific form of the intermediate (rarely metastasizing) fibroblastic and myofibroblastic tumors and other variants of this disorder as a specific form of the intermediate (locally aggressive ...
The white tumor infiltrates the adjacent skeletal muscle (red tissue – lower left) and fat (yellow tissue – upper left). This tendency for invasion of adjacent normal tissues and structures is the reason that desmoid-type fibromatosis has a relatively high rate of local recurrence, even after surgical removal. Specialty: Oncology