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  2. Grapefruit can interfere with your medications — here's what ...

    www.aol.com/lifestyle/grapefruit-interfere...

    A single glass of grapefruit juice can interfere with your body's ability to break down a medication. ... "Many food-drug interactions and potential side effects can be avoided by following ...

  3. List of adverse effects of venlafaxine - Wikipedia

    en.wikipedia.org/wiki/List_of_adverse_effects_of...

    Headache — an often transient side effect that is common to most serotonin reuptake inhibitors and that most often occurs at the beginning of therapy or after a dose escalation. Nausea — an adverse effect that is more common with venlafaxine than with the SSRIs. Usually transient and less severe in those receiving the extended release ...

  4. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    Analgesic and behavioral effects were reported for 12 hours and plasma samples were analyzed for oxycodone metabolites for 48 hours. Grapefruit juice increased the mean area under the oxycodone concentration-time curve (AUC(0-∞)) by 1.7 fold, the peak plasma concentration by 1.5-fold and the half-life of oxycodone by 1.2-fold as compared to ...

  5. Venlafaxine - Wikipedia

    en.wikipedia.org/wiki/Venlafaxine

    A rare but serious side effect of venlafaxine is liver injury. It appears to affect both male and female patients with a median age of 44. Cessation of venlafaxine is one of the appropriate measures of management. While the mechanism of venlafaxine-related liver injury remains unclear, findings suggest that it may be related to a CYP2D6 ...

  6. Switching Antidepressants: Safety, Side Effects & Other ... - AOL

    www.aol.com/switching-antidepressants-safety...

    Despite their side effects, some tricyclic antidepressants may be effective for improving depression symptoms when other, newer medications aren’t effective. Atypical antidepressants.

  7. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs. Interactions may occur by simultaneous targeting of receptors , directly or indirectly. For example, both Zolpidem and alcohol affect GABA A receptors , and their simultaneous consumption results in the overstimulation of the receptor, which can ...

  8. Which Antidepressants Can Cause ED? - AOL

    www.aol.com/antidepressants-cause-ed-105700786.html

    A not-so-fun fact: Intimate dysfunction often occurs as a side effect of antidepressants. In men, the side effects of antidepressants result in reduced drive (low libido) or lowered desire ...

  9. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...

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