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Glycolysis is the metabolic pathway that converts glucose (C 6 H 12 O 6) into pyruvate and, in most organisms, occurs in the liquid part of cells (the cytosol). The free energy released in this process is used to form the high-energy molecules adenosine triphosphate (ATP) and reduced nicotinamide adenine dinucleotide (NADH). [ 1 ]
Alcoholic fermentation is often used by plants in anaerobic conditions to produce ATP and regenerate NAD + to allow for glycolysis to continue. For most plant tissues, fermentation only occurs in anaerobic conditions, but there are a few exceptions.
This enzyme has been studied primarily in plants, but it has been studied in some bacteria as well. [1] It is a key enzyme in gluconeogenesis and photosynthesis that is responsible for reversing the reaction performed by pyruvate kinase in Embden-Meyerhof-Parnas glycolysis. It should not be confused with pyruvate, water dikinase.
Pyruvate from glycolysis [18] undergoes a simple redox reaction, forming lactic acid. [19] [20] Overall, one molecule of glucose (or any six-carbon sugar) is converted to two molecules of lactic acid: C 6 H 12 O 6 → 2 CH 3 CHOHCOOH. It occurs in the muscles of animals when they need energy faster than the blood can supply oxygen.
Cellular respiration is a vital process that occurs in the cells of all [[plants and some bacteria ]]. [ 2 ] [ better source needed ] Respiration can be either aerobic, requiring oxygen, or anaerobic; some organisms can switch between aerobic and anaerobic respiration.
Glycolysis results in the breakdown of glucose, but several reactions in the glycolysis pathway are reversible and participate in the re-synthesis of glucose (gluconeogenesis). [9] Glycolysis was the first metabolic pathway discovered: As glucose enters a cell, it is immediately phosphorylated by ATP to glucose 6-phosphate in the irreversible ...
In vertebrates, gluconeogenesis occurs mainly in the liver and, to a lesser extent, in the cortex of the kidneys. It is one of two primary mechanisms – the other being degradation of glycogen ( glycogenolysis ) – used by humans and many other animals to maintain blood sugar levels , avoiding low levels ( hypoglycemia ). [ 7 ]
Major metabolic pathways that occur in the cytosol in animals are protein biosynthesis, the pentose phosphate pathway, glycolysis and gluconeogenesis. [66] The localization of pathways can be different in other organisms, for instance fatty acid synthesis occurs in chloroplasts in plants [67] [68] and in apicoplasts in apicomplexa. [69]