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  2. Prescription drug overuse - Wikipedia

    en.wikipedia.org/wiki/Prescription_drug_overuse

    Opioids, such as fentanyl, morphine, and oxycodone, are used to treat post-surgery pain and chronic pain. [6] Opioids work by affecting the brain cells and reducing the perception of pain. [7] Other side effects include euphoria, mood changes, and the clouding or complete loss of consciousness. [8]

  3. Speedball (drug) - Wikipedia

    en.wikipedia.org/wiki/Speedball_(drug)

    Speedball, powerball, or over and under [1] is the polydrug mixture of a stimulant with a depressant, usually an opioid.The most well-known mixture used for recreational drug use is that of cocaine and heroin; however, amphetamines can also be mixed with morphine and/or fentanyl.

  4. Opioid withdrawal - Wikipedia

    en.wikipedia.org/wiki/Opioid_withdrawal

    A major feature of opioid withdrawal is exacerbated noradrenaline release in the locus coeruleus. Alpha-2 adrenergic receptor agonists can be used to manage the symptoms of acute withdrawal. Lofexidine and clonidine are used for this purpose; both are considered to be equally effective, though clonidine has more side effects than lofexidine. [16]

  5. As the opioid epidemic evolves, impacts bleed into cocaine ...

    www.aol.com/news/2017-01-03-as-the-opioid...

    America’s opioid epidemic is fueling a startling increase in cocaine-related overdose deaths in recent years, as users mix deadly cocktails. As the opioid epidemic evolves, impacts bleed into ...

  6. Antibiotic misuse - Wikipedia

    en.wikipedia.org/wiki/Antibiotic_misuse

    Antibiotic misuse can lead to resistance in harmless bacteria that can be shared with other bacteria, or create an opportunity for potentially harmful bacteria to replace the harmless ones. [ 37 ] Official guidelines by the American Heart Association for dental antibiotic prophylaxis call for the administration of antibiotics to prevent ...

  7. Hotel Cocaine Stars Answer Our Burning Q: How Do You Fake ...

    www.aol.com/hotel-cocaine-stars-answer-burning...

    Now that we’re a few episodes into MGM+’s Hotel Cocaine, it’s time to answer the question: How do the members of the 1970s drama fake-snort all that prop powder?. Answer, according to Mark ...

  8. Laudanum - Wikipedia

    en.wikipedia.org/wiki/Laudanum

    Side effects of laudanum are generally the same as with morphine, and include euphoria, dysphoria, pruritus, sedation, constipation, reduced tidal volume, respiratory depression, as well as psychological dependence, physical dependence, miosis, and xerostomia. Overdose can result in severe respiratory depression or collapse and death.

  9. Opioid overdose - Wikipedia

    en.wikipedia.org/wiki/Opioid_overdose

    Naloxone works by temporarily blocking the effects of opioids, including respiratory depression and sedation. [49] [3] Naloxone is safe and side effects are rare, generally limited to allergic reactions. [50] It should be given if there is any suspicion of an opioid overdose.