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  2. Clark's rule - Wikipedia

    en.wikipedia.org/wiki/Clark's_rule

    The procedure is to take the child's weight in pounds, divide by 150 lb, and multiply the fractional result by the adult dose to find the equivalent child dosage.For example, if an adult dose of medication calls for 30 mg and the child weighs 30 lb, divide the weight by 150 (30/150) to obtain 1/5 and multiply 1/5 times 30 mg to get 6 mg.

  3. Belimumab - Wikipedia

    en.wikipedia.org/wiki/Belimumab

    Belimumab, sold under the brand name Benlysta, is a human monoclonal antibody that inhibits B-cell activating factor (BAFF), [6] also known as B-lymphocyte stimulator (BLyS). [7] It is approved in the United States [ 8 ] and Canada, [ 9 ] and the European Union [ 5 ] to treat systemic lupus erythematosus and lupus nephritis.

  4. Maintenance dose - Wikipedia

    en.wikipedia.org/wiki/Maintenance_dose

    In pharmacokinetics, a maintenance dose is the maintenance rate [mg/h] of drug administration equal to the rate of elimination at steady state. This is not to be confused with dose regimen , which is a type of drug therapy in which the dose [mg] of a drug is given at a regular dosing interval on a repetitive basis.

  5. Loading dose - Wikipedia

    en.wikipedia.org/wiki/Loading_dose

    So, the maintenance dose of foosporin is 100 milligrams (100 mg) per day—just enough to offset the amount cleared. Suppose a patient just started taking 100 mg of foosporin every day. On the first day, they'd have 100 mg in their system; their body would clear 10 mg, leaving 90 mg.

  6. Area under the curve (pharmacokinetics) - Wikipedia

    en.wikipedia.org/wiki/Area_under_the_curve...

    Absolute bioavailability refers to the bioavailability of a drug when administered via an extravascular dosage form (i.e. oral tablet, suppository, subcutaneous, etc.) compared with the bioavailability of the same drug administered intravenously (IV). This is done by comparing the AUC of the non-intravenous dosage form with the AUC for the drug ...

  7. Effective dose (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Effective_dose_(pharmacology)

    The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...

  8. Expanded Program on Immunization (Philippines) - Wikipedia

    en.wikipedia.org/wiki/Expanded_Program_on...

    Vaccine combinations (few exceptions), antibiotics, low-dose steroids (less than 20 mg per day), minor infections with low fever (below 38.5º Celsius), diarrhea, malnutrition, kidney or liver disease, heart or lung disease, non-progressive encephalopathy, well controlled epilepsy or advanced age, are not contraindications to vaccination.

  9. Reference dose - Wikipedia

    en.wikipedia.org/wiki/Reference_dose

    A reference dose is the United States Environmental Protection Agency's maximum acceptable oral dose of a toxic substance, "below which no adverse noncancer health effects should result from a lifetime of exposure". Reference doses have been most commonly determined for pesticides. The EPA defines an oral reference dose (abbreviated RfD) as: