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Flibanserin, sold under the brand name Addyi, is a medication approved for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD). [4] [5] The medication improves sexual desire, increases the number of satisfying sexual events, and decreases the distress associated with low sexual desire. [6]
Due to a wide range of observed side-effects, flibanserin's safety has been called into question. Clinical trials reported adverse reactions including dizziness, nausea, fatigue, and insomnia. [16] Hypotension and central nervous system depression (somnolence) leading to sedation and sleepiness symptoms were also observed. [16]
Common side effects include nausea, pain at the site of injection, and headache. [2] It may also cause a temporary increase in blood pressure and decrease in heart rate after each dose, and darkening of the gums, face, and breasts. [4] The medication is a peptide and acts by activating the melanocortin receptors. [1] [5]
Currently, there are two such FDA-approved medications — Addyi (flibanserin) and Vyleesi (bremelanotide) — and some physicians will also prescribe testosterone, as well as the antianxiety drug ...
Dr. Jennifer Wider, a women’s health expert, tells Yahoo Life, “There are many reasons why women can have a lower sex drive, including depression, anxiety, stress, side effects from a ...
While it is effective for some women, it has been criticized for its limited efficacy, and has many warnings and contraindications that limit its use. [69] Flibanserin was found to increase pleasurable sexual experiences by 0.5 events per month in trials. Possible side effects include dizziness, drowsiness, nausea and fatigue. [51]
Cialis has several common side effects, many of which also happen with other drugs used to treat ED, like sildenafil (generic Viagra®), vardenafil , and avanafil (Stendra®).
The side effects on sexual functioning can impact mental health and quality of life. [36] However, the decrease in depressive symptoms from antidepressants make it worth the sexual side effects for many people. They can be managed by changing the dose, switching drugs, or taking "antidotes". [37]