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  2. Nucleus accumbens - Wikipedia

    en.wikipedia.org/wiki/Nucleus_accumbens

    The nucleus accumbens shell (NAcc shell) is a substructure of the nucleus accumbens. The shell and core together form the entire nucleus accumbens. Location: The shell is the outer region of the nucleus accumbens, and – unlike the core – is considered to be part of the extended amygdala, located at its rostral pole.

  3. Mesolimbic pathway - Wikipedia

    en.wikipedia.org/wiki/Mesolimbic_pathway

    The nucleus accumbens and olfactory tubercle are located in the ventral striatum and are primarily composed of medium spiny neurons. [9] [12] [13] The nucleus accumbens is subdivided into limbic and motor subregions known as the NAcc shell and NAcc core. [11]

  4. Ventral tegmental area - Wikipedia

    en.wikipedia.org/wiki/Ventral_tegmental_area

    The ventral tegmental area (VTA) (tegmentum is Latin for covering), also known as the ventral tegmental area of Tsai, [1] or simply ventral tegmentum, is a group of neurons located close to the midline on the floor of the midbrain. The VTA is the origin of the dopaminergic cell bodies of the mesocorticolimbic dopamine system and other dopamine ...

  5. Brain stimulation reward - Wikipedia

    en.wikipedia.org/wiki/Brain_stimulation_reward

    The nucleus accumbens is located in the ventral striatum and integrates information from cortical and limbic brain structures to mediate behaviors the reinforce reward. [16] It is a major target for the dopaminergic projections from the VTA, a group of neurons located close to the midline on the floor of the midbrain .

  6. Dopaminergic pathways - Wikipedia

    en.wikipedia.org/wiki/Dopaminergic_pathways

    The mesolimbic pathway transmits dopamine from the ventral tegmental area (VTA), which is located in the midbrain, to the ventral striatum, which includes both the nucleus accumbens and olfactory tubercle. [5] [6] The "meso" prefix in the word "mesolimbic" refers to the midbrain, or "middle brain", since "meso" means "middle" in Greek.

  7. Basal ganglia - Wikipedia

    en.wikipedia.org/wiki/Basal_ganglia

    The subthalamic nucleus is a diencephalic gray matter portion of the basal ganglia, and the only portion of the ganglia that produces an excitatory neurotransmitter, glutamate. The role of the subthalamic nucleus is to stimulate the SNr-GPi complex and it is part of the indirect pathway. The subthalamic nucleus receives inhibitory input from ...

  8. Basal forebrain - Wikipedia

    en.wikipedia.org/wiki/Basal_forebrain

    Basal forebrain. Part of the human brain, the basal forebrain structures are located in the forebrain to the front of and below the striatum. They include the ventral basal ganglia (including nucleus accumbens and ventral pallidum), nucleus basalis, diagonal band of Broca, substantia innominata, and the medial septal nucleus. These structures ...

  9. Limbic system - Wikipedia

    en.wikipedia.org/wiki/Limbic_system

    In 1954, Olds and Milner found that rats with metal electrodes implanted into their nucleus accumbens, as well as their septal nuclei, repeatedly pressed a lever activating this region. [12] The limbic system also interacts with the basal ganglia. The basal ganglia are a set of subcortical structures that direct intentional movements.