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  2. Node of Ranvier - Wikipedia

    en.wikipedia.org/wiki/Node_of_Ranvier

    Furthermore, Lambert et al. and Eshed et al. also indicates that neurofascin accumulates before Nav channels and is likely to have crucial roles in the earliest events associated with node of Ranvier formation. Thus, multiple mechanisms may exist and work synergistically to facilitate clustering of Nav channels at nodes of Ranvier.

  3. Cardiac conduction system - Wikipedia

    en.wikipedia.org/wiki/Cardiac_conduction_system

    An impulse (action potential) that originates from the SA node at a relative rate of 60–100 bpm is known as a normal sinus rhythm. If SA nodal impulses occur at a rate less than 60 bpm, the heart rhythm is known as sinus bradycardia. If SA nodal impulses occur at a rate exceeding 100 bpm, the consequent rapid heart rate is sinus tachycardia ...

  4. Cardiac pacemaker - Wikipedia

    en.wikipedia.org/wiki/Cardiac_pacemaker

    The sinoatrial node (SA node) is the primary pacemaker of the heart. It is a region of cardiac muscle on the wall of the upper right atrium near to the superior vena cava entrance. The cells that make up the SA node are specialized cardiomyocytes known as pacemaker cells that can spontaneously generate cardiac action potentials.

  5. Atrioventricular node - Wikipedia

    en.wikipedia.org/wiki/Atrioventricular_node

    The atrioventricular node or AV node electrically connects the heart's atria and ventricles to coordinate beating in the top of the heart; it is part of the electrical conduction system of the heart. [1] The AV node lies at the lower back section of the interatrial septum near the opening of the coronary sinus, and conducts the normal ...

  6. Saltatory conduction - Wikipedia

    en.wikipedia.org/wiki/Saltatory_conduction

    Myelinated axons only allow action potentials to occur at the unmyelinated nodes of Ranvier that occur between the myelinated internodes. It is by this restriction that saltatory conduction propagates an action potential along the axon of a neuron at rates significantly higher than would be possible in unmyelinated axons (150 m/s compared from 0.5 to 10 m/s). [1]

  7. Internodal segment - Wikipedia

    en.wikipedia.org/wiki/Internodal_segment

    An internodal segment (or internode) is the portion of a nerve fiber between two Nodes of Ranvier. The neurolemma or primitive sheath is not interrupted at the nodes, but passes over them as a continuous membrane.

  8. Cardiac cycle - Wikipedia

    en.wikipedia.org/wiki/Cardiac_cycle

    The rhythmic sequence (or sinus rhythm) of this signaling across the heart is coordinated by two groups of specialized cells, the sinoatrial (SA) node, which is situated in the upper wall of the right atrium, and the atrioventricular (AV) node located in the lower wall of the right heart between the atrium and ventricle.

  9. Sinoatrial node - Wikipedia

    en.wikipedia.org/wiki/Sinoatrial_node

    The sinoatrial node (also known as the sinuatrial node, SA node or sinus node) is an oval shaped region of special cardiac muscle in the upper back wall of the right atrium made up of cells known as pacemaker cells. The sinus node is approximately 15 mm long, 3 mm wide, and 1 mm thick, located directly below and to the side of the superior vena ...