Search results
Results from the WOW.Com Content Network
Conivaptan hydrochloride is an off-white or a pale yellow power with a solubility of 0.25 mg/mL in water at 23 °C. The injectable formulation consists of 20 mg conivaptan hydrochloride, 0.4 g ethanol, 1.2 g propylene glycol and water. [2]
Tolvaptan, sold under the brand name Samsca among others, is an aquaretic drug that functions as a selective, competitive vasopressin receptor 2 (V 2) antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
Tolvaptan phosphate is a drug used for the treatment of cardiac edema. It is a prodrug of tolvaptan , [ 1 ] [ 2 ] formulated as the salt tolvaptan sodium phosphate, for intravenous administration .
The "vaptan" drugs act by directly blocking the action of vasopressin at its receptors (V 1A, V 1B and V 2).These receptors have a variety of functions, with the V 1A and V 2 receptors are expressed peripherally and involved in the modulation of blood pressure and kidney function respectively, while the V 1A and V 1B receptors are expressed in the central nervous system.
Tolvaptan was studied in DILIsym®, a state of the art, multiscale computational model that uses non-clinical and clinical drug data to predict whether a drug could cause idiosyncratic liver toxicity. [16] DILIsym® replicated accurately the liver toxicity observed with tolvaptan in clinical studies. [17]
This is an accepted version of this page This is the latest accepted revision, reviewed on 5 February 2025. Economy of Bangladesh Motijheel C/A, the downtown of Dhaka Currency Bangladeshi taka (BDT, ৳) Fiscal year 1 July – 30 June Trade organizations SAFTA, SAARC, BIMSTEC, WTO, AIIB, IMF, Commonwealth of Nations, World Bank, ADB, Developing-8 Country group Developing/Emerging Lower-middle ...
A sole-source contract was awarded to Population Services International (PSI), which then signed an agreement with the Government of Bangladesh establishing the activity as a parasternal one, with a project council serving as the board of directors. [3] In 1990, it became a company governed by a board of directors made out of volunteers. [4]
Active Bangladesh military aircraft is a list of military aircraft that are used by the Bangladesh Armed Forces. For aircraft no longer in-service see: List of historic Bangladesh military aircraft. Approximately 80 aircraft and five Mil Mi-17 were destroyed by the devastating 1991 Bangladesh cyclone.