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Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). [2] [3] [4]Salts of this anion, especially docusate sodium, are widely used in medicine as an emollient laxative and as stool softeners, by mouth or rectally. [1]
The aldohexose that is most important in biochemistry is D-glucose, which is the main "fuel" for metabolism in many living organisms. The 2-ketohexoses psicose, fructose and tagatose occur naturally as the D-isomers, whereas sorbose occurs naturally as the L-isomer. D-Sorbose is commonly used in the commercial synthesis of ascorbic acid. [10]
Studies have shown that milk and molasses enemas have a low complication rate when used in the emergency department [20] and are safe and effective with minimal side effects. [ 21 ] Mineral oil functions as a lubricant and stool softener, but may have side effects including rectal skin irritation and leakage of oil.
Mannose differs from glucose by inversion of the C-2 chiral center. Mannose displays a pucker in the solution ring form. This simple change leads to the drastically different biochemistry of the two hexoses. This change has the same effect on the other aldohexoses, as well.
The systematic name of this enzyme class is GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming). Other names in common use include guanosine 5'-diphosphate- D -mannose oxidoreductase , guanosine diphosphomannose oxidoreductase , guanosine diphosphomannose 4,6-dehydratase , GDP- D -mannose dehydratase , GDP- D -mannose 4,6 ...
The 3 substrates of this enzyme are GDP-D-mannose, NAD +, and H 2 O, whereas its 3 products are GDP-D-mannuronate, NADH, and H +. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD + or NADP + as acceptor. The systematic name of this enzyme class is GDP-D-mannose:NAD + 6 ...
The 3 substrates of this enzyme are GDP-6-deoxy-D-mannose, NAD +, and NADP +, whereas its 4 products are GDP-4-dehydro-6-deoxy-D-mannose, NADH, NADPH, and H +. This enzyme belongs to the family of oxidoreductases , specifically those acting on the CH-OH group of donor with NAD + or NADP + as acceptor.