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Increase in phospholipase A 2 activity is an acute-phase reaction that rises during inflammation, which is also seen to be exponentially higher in low back disc herniations compared to rheumatoid arthritis. [citation needed] It is a mixture of inflammation and substance P that are responsible for pain. [citation needed]
18786 Ensembl ENSG00000137055 ENSMUSG00000028577 UniProt Q9Y263 P27612 RefSeq (mRNA) NM_001031689 NM_004253 NM_001321546 NM_172695 RefSeq (protein) NP_001026859 NP_001308475 NP_766283 Location (UCSC) Chr 9: 26.9 – 26.95 Mb Chr 4: 94.46 – 94.49 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Phospholipase A-2-activating protein is an enzyme that in humans is encoded by the PLAA ...
Endothelial lipase is primarily a phospholipase. [2] Phospholipase A 2 acts on the intact lecithin molecule and hydrolyzes the fatty acid esterified to the second carbon atom. The resulting products are lysolecithin and a fatty acid. Phospholipase A 2 is an enzyme present in the venom of bees, blennies and viper snakes. [3]
Phospholipase A 2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals as well as fish. [7] Sequences of pancreatic PLA 2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is ...
5321 18783 Ensembl ENSG00000116711 ENSMUSG00000056220 UniProt P47712 P47713 RefSeq (mRNA) NM_001311193 NM_024420 NM_008869 NM_001305632 RefSeq (protein) NP_001298122 NP_077734 NP_001292561 NP_032895 Location (UCSC) Chr 1: 186.83 – 186.99 Mb Chr 1: 149.71 – 149.84 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cytosolic phospholipase A 2 is an enzyme that in humans is encoded by ...
AdPLA is encoded by a 1.3 kilobase AdPLA messenger RNA and is an 18 kDa protein. It belongs to a superfamily of phospholipase A2 (PLA2) enzymes and is found primarily in adipose tissue. AdPLA regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to ...
Lipoprotein-associated phospholipase A 2 (Lp-PLA 2) also known as platelet-activating factor acetylhydrolase (PAF-AH) is a phospholipase A 2 enzyme that in humans is encoded by the PLA2G7 gene. [5] [6] Lp-PLA 2 is a 45-kDa protein of 441 amino acids. [7] It is one of several PAF acetylhydrolases.
5322 18784 Ensembl ENSG00000127472 ENSMUSG00000041193 UniProt P39877 P97391 RefSeq (mRNA) NM_000929 NM_001122954 NM_011110 RefSeq (protein) NP_000920 NP_001116426 NP_035240 Location (UCSC) Chr 1: 20.03 – 20.09 Mb Chr 4: 138.53 – 138.59 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Calcium-dependent phospholipase A 2 is an enzyme that in humans is encoded by the PLA2G5 gene ...