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Vitamin K is a family of structurally similar, fat-soluble vitamers found in foods and marketed as dietary supplements. [1] The human body requires vitamin K for post-synthesis modification of certain proteins that are required for blood coagulation ("K" from Danish koagulation, for "coagulation") or for controlling binding of calcium in bones and other tissues. [2]
Vitamin K2 may have a protective effect on bone mineral density and reduced risk of hip, vertebral and non-vertebral fractures. [11] These effects appear to be accentuated when combined with vitamin D and in the setting of osteoporosis. [1] Research suggests that vitamin K 2 (Menaquinone 7, MK-7]) may reduce the rate and severity of night time ...
Vitamin K1 (phylloquinone): Found in leafy green vegetables, vitamin K1 assists with heart health and proper blood clotting. Vitamin K2 (menaquinone): Vitamin K2 supports bone and heart health ...
Vitamin K 1-deficiency may occur by disturbed intestinal uptake (such as would occur in a bile duct obstruction), by therapeutic or accidental intake of a vitamin K 1-antagonist such as warfarin, or, very rarely, by nutritional vitamin K 1 deficiency. As a result, Gla-residues are inadequately formed and the Gla-proteins are insufficiently active.
Vitamin K2 is lauded for a number of important health benefits. But taking too much can be dangerous, health experts say.
There are two primary types of vitamin K: vitamin K1 and vitamin K2. “Vitamin K1 plays an important role in blood clotting, while K2 is more important for bone health, regulation of cell growth ...
4256 17313 Ensembl ENSG00000111341 ENSMUSG00000030218 UniProt P08493 P19788 RefSeq (mRNA) NM_001190839 NM_000900 NM_008597 RefSeq (protein) NP_000891 NP_001177768 NP_032623 Location (UCSC) Chr 12: 14.88 – 14.89 Mb Chr 6: 136.85 – 136.85 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Matrix Gla protein (MGP) is member of a family of vitamin K 2 dependent, Gla -containing proteins ...
Hypocalcemia (low blood calcium) and hypercalcemia (high blood calcium) are both serious medical disorders. Osteoporosis, osteomalacia and rickets are bone disorders linked to calcium metabolism disorders and effects of vitamin D. Renal osteodystrophy is a consequence of chronic kidney failure related to the calcium metabolism.
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