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After its discovery, amphetamine was purified and put into medical use in the 1900s. [5] Amphetamine was originally sold as a decongestant inhaler in the United States in 1933 and led to widespread ATS abuse in military forces and civilians later on. [5] The details of history of amphetamine can be found here.
Stimulant use disorder is a type of substance use disorder where the use of stimulants caused clinically significant impairment or distress. It is defined in the DSM-5 as "the continued use of amphetamine -type substances, cocaine , or other stimulants leading to clinically significant impairment or distress, from mild to severe". [ 1 ]
Amphetamine dependence has shown to have the highest remission rate compared to cannabis, cocaine, and opioids. [9] Severe withdrawal associated with dependence from recreational substituted amphetamine use can be difficult for a user to cope with. [10] [11] [12] Long-term use of certain substituted amphetamines, particularly methamphetamine ...
At high doses, prescription amphetamines, used to treat ADHD could increase a person’s risk of psychosis. Image credit: visualspace/Getty Images.
Drugs in the class of amphetamines, or substituted amphetamines, are known to induce "amphetamine psychosis" typically when chronically abused or used in high doses. [8] In an Australian study of 309 active methamphetamine users, 18% had experienced a clinical level psychosis in the past year. [9]
The first stop is his mother’s modular home in Hermosa, just south of the city, where he will change cars. In the distance, the lights of Rapid City are mostly dark or blinking like strings of busted Christmas tree lights. The road is covered in snow, and Fischer can’t see a thing. He fingers his patchy beard and talks at double speed.
A New Jersey driver who was arrested by a trooper who thought she was drunk when she was really having a stroke — delaying urgent medical care by hours — has been awarded nearly $13 million.
Addiction is a serious risk with heavy recreational amphetamine use, but is unlikely to occur from long-term medical use at therapeutic doses. Very high doses can result in psychosis (e.g., hallucinations , delusions and paranoia ) which rarely occurs at therapeutic doses even during long-term use.