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Antibiotic cover is only considered when undergoing invasive dental procedures. [5] If no antibiotic cover is needed, manage the patient as if they were at normal risk of IE; If antibiotic cover is needed, discuss with the patient about pros & cons of antibiotic prophylaxis to obtain informed consent about their management.
Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
Antibiotics is a peer-reviewed open-access scientific journal covering various aspects of antibiotics research. It is published by MDPI and was established in 2012. The editor-in-chief is Nicholas Dixon ( University of Wollongong ).
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Self-prescribing of antibiotics is an example of misuse. [106] Many antibiotics are frequently prescribed to treat symptoms or diseases that do not respond to antibiotics or that are likely to resolve without treatment. Also, incorrect or suboptimal antibiotics are prescribed for certain bacterial infections.
Diagram depicting antibiotic resistance through alteration of the antibiotic's target site, modeled after MRSA's resistance to penicillin. Beta-lactam antibiotics permanently inactivate PBP enzymes, which are essential for cell wall synthesis and thus for bacterial life, by permanently binding to their active sites. Some forms of MRSA, however ...
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