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A cellular model is a mathematical model of aspects of a biological cell, for the purposes of in silico research. Developing such models has been a task of systems biology and mathematical biology .
Efforts made toward the development of micro fabricated cell culture systems that aim to create models that replicate aspects of the human body as closely as possible and give examples that demonstrate their potential use in drug development, such as identifying synergistic drug interactions as well as simulating multi-organ metabolic interactions.
Human Cell Atlas; Content; Description: The Human Cell Atlas is a global consortium that is creating detailed maps of the cells in the human body to transform understanding of health and disease. Organisms: Human: Contact; Primary citation: Regev, Aviv; et al. (Human Cell Atlas Organizing Committee) (2018). "The Human Cell Atlas White Paper".
Modelling biological systems is a significant task of systems biology and mathematical biology. [a] Computational systems biology [b] [1] aims to develop and use efficient algorithms, data structures, visualization and communication tools with the goal of computer modelling of biological systems.
The Human Cell Atlas project, which started in 2016, had as one of its goals to "catalog all cell types (for example, immune cells or brain cells) and sub-types in the human body". [13] By 2018, the Human Cell Atlas description based the project on the assumption that "our characterization of the hundreds of types and subtypes of cells in the ...
The project was headed by the founding director Henry Markram—who also launched the European Human Brain Project—and was co-directed by Felix Schürmann, Adriana Salvatore and Sean Hill. Using a Blue Gene supercomputer running Michael Hines's NEURON , the simulation involved a biologically realistic model of neurons [ 1 ] [ 2 ] [ 3 ] and an ...
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The LaTeX source code is attached to the PDF file (see imprint). Licensing Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation License , Version 1.2 or any later version published by the Free Software Foundation ; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover ...