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As a cream it is used for actinic keratosis, basal cell carcinoma, and skin warts. [4] [5] Side effects of use by injection are common. [3] They may include inflammation of the mouth, loss of appetite, low blood cell counts, hair loss, and inflammation of the skin. [3] When used as a cream, irritation at the site of application usually occurs. [4]
Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
Lomustine may be administered orally or by injection in cats and dogs. This chemotherapy has been observed to have a variety of side effects in animals, paralleling those in humans, including but not limited to bone marrow immunosuppression, gastrointestinal issues, and hepatotoxicity. [12]
Common side effects include fever, weight loss, vomiting, and rash. [6] A severe type of anaphylaxis may occur. [6] It may also cause inflammation of the lungs that can result in lung scarring. [6] Chest X-rays every couple of weeks are recommended to check for this. [6] Bleomycin may cause harm to the baby if used during pregnancy. [6]
The overwhelming majority of neutrophilic eccrine hidradenitis (NEH) is seen in people with cancer, especially leukaemia, who receive chemotherapy with a cytotoxic drug. These include: Bleomycin , chlorambucil , cyclophosphamide , cytarabine , doxorubicin , lomustine , mitoxantrone , topotecan , and vincristine .
Side effects of thalidomide-induced peripheral neuropathy include sensory symptoms, possible motor impairment, and gastrointestinal and cardiovascular autonomic manifestations. The symptoms of immunomodulatory drugs may dictate whether treatment is continued or discontinued, and they can last long-term after chemotherapy completion. [3]
Steroidogenesis.Trilostane inhibits 3β-HSD. Trilostane is a steroidogenesis inhibitor. [1] It is specifically an inhibitor of 3β-hydroxysteroid dehydrogenase (3β-HSD). [1] [15] As a result of this action, trilostane blocks the conversion of Δ 5-3β-hydroxysteroids, including pregnenolone, 17α-hydroxypregnenolone, dehydroepiandrosterone (DHEA), and androstenediol, into Δ 4-3-ketosteroids ...
The most common side effects of podophyllotoxin cream are typically limited to irritation of tissue surrounding the application site, usually burning, redness, pain, itching, and swelling. [14] Application is sometimes immediately followed by burning or itching. Small sores, itching, and peeling skin may also follow.